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Chorionic gonadotropin alpha | CGA |
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 | | | Pengidentifikasi |
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| Alias | CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA, Chorionic gonadotropin alpha, glycoprotein hormones, alpha polypeptide, Alpha subunit of glycoprotein hormones, GPA1 |
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| ID eksternal | OMIM: 118850 MGI: 88390 HomoloGene: 587 GeneCards: CGA |
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| | Ontologi gen |
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| Fungsi molekuler | • GO:0001948, GO:0016582 Ikatan protein plasma
• hormone activity
• follicle-stimulating hormone activity
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| Komponen seluler | • Golgi lumen
• extracellular region
• extracellular space
• follicle-stimulating hormone complex
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| Proses biologis | • cell-cell signaling
• peptide hormone processing
• positive regulation of cell population proliferation
• GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
• GO:0072468 signal transduction
• positive regulation of cell migration
• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
• regulation of signaling receptor activity
• G protein-coupled receptor signaling pathway
• positive regulation of steroid biosynthetic process
• thyroid hormone generation
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| Sumber:Amigo / QuickGO |
| | Ortolog |
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| Spesies | Manusia | Tikus |
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| Entrez | | |
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| Ensembl | | |
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| UniProt | | |
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| RefSeq (mRNA) | | |
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| RefSeq (protein) | | |
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| Lokasi (UCSC) | n/a | n/a |
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| Pencarian PubMed | [1] | [2] |
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| Wikidata | |
CGA adalah nama berkas gen pada kromosom 6 lokasi 6q12-q21.[3]
Empat hormon glikoprotein yakni gonadotropin, lutropin, FSH, TSH merupakan protein dimer yang terdiri dari sub-unit alfa dan beta. CGA merupakan berkas gen yang mengekspresikan protein sub-unit alfa yang identik untuk keempat hormon tersebut, sedangkan sub-unit beta diekspresikan oleh berkas gen yang berlainan.
Rujukan
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