Pimozida
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| Data klinis | |
|---|---|
| Nama dagang | Orap |
| AHFS/Drugs.com | monograph |
| MedlinePlus | a686018 |
| License data | |
| Kategori kehamilan |
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| Rute pemberian | Oral |
| Kelas obat | Typical antipsychotic |
| Kode ATC | |
| Status hukum | |
| Status hukum | |
| Data farmakokinetika | |
| Bioavailabilitas | 40-50% |
| Metabolisme | CYP3A4, CYP1A2 dan CYP2D6 |
| Waktu paruh eliminasi | 55 jam (dewasa), 66 jam (anak-anak) |
| Ekskresi | Urin |
| Pengenal | |
| |
| Nomor CAS | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.016.520 |
| Data sifat kimia dan fisik | |
| Rumus | C28H29F2N3O |
| Massa molar | 461,56 g·mol−1 |
| Model 3D (JSmol) | |
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| (verify) | |
Pimozida adalah salah satu obat antipsikotik. Obat ini bekerja dengan memblokir reseptor dopaminergik di tingkat neuron. Obat ini juga memblokir reseptor muskarinik, alfa-1, dan histamin H1. Obat ini diindikasikan untuk pasien dengan sindrom Gilles de la Tourette, gangguan spektrum autisme, demensia, dan penyakit Huntington.[2]
Referensi
- ^ Anvisa (2023-03-31). "RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial" [Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (dalam bahasa Brazilian Portuguese). Diário Oficial da União (dipublikasikan 2023-04-04). Diarsipkan dari versi aslinya tanggal 2023-08-03. Diakses tanggal 2023-08-16.
- ^ http://www.prvademecum.com/PrVademecum_Bra/PRData/NEWPrincipioActivo.asp?D=1309. ; ; ; Templat:Ligação inativa
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