Stigmastanol
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| Nama | |
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| Nama IUPAC
5α-Stigmastan-3β-ol
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| Nama IUPAC (sistematis)
(1R,3aS,3bR,5aS,7S,9aS,9bS,11aR)-1-[(2R,5R)-5-Etil-6-metilheptan-2-il]-9a,11a-dimetilheksadekahidro-1H-siklopenta[a]fenantren-7-ol | |
| Nama lain
(3β)-Stigmastan-3-ol; (3β,5α)-Stigmastan-3-ol; β-Sitostanol; Dihidrositosterin; Dihidrositosterol; Dihidro-β-sitosterol; Fukostanol; Spinastanol; 24α-Etilkolestanol
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| Penanda | |
Model 3D (JSmol)
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| Nomor EC | |
PubChem CID
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| Nomor RTECS | {{{value}}} |
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CompTox Dashboard (EPA)
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| Sifat | |
| C29H52O | |
| Massa molar | 416,73 g·mol−1 |
| Titik didih | 139,4 hingga 139,8 °C (282,9 hingga 283,6 °F; 412,5 hingga 412,9 K)[1] |
Kecuali dinyatakan lain, data di atas berlaku pada suhu dan tekanan standar (25 °C [77 °F], 100 kPa). | |
| Referensi | |
Stigmastanol atau sitostanol adalah fitosterol yang ditemukan dalam berbagai sumber tumbuhan. Mirip dengan ester sterol dan ester stanol, stigmastanol menghambat penyerapan kolesterol dari makanan.[2][3][4]
Stigmastanol adalah produk dari reduksi β-sitosterol[5] dan hidrogenasi stigmasterol.[6]
Lihat juga
- Stigmasterol, sterol yang terkait erat
Referensi
- ^ Sandqvist, Hakan; Bengtsson, Edvard (1931). "The empirical formula of sitosterol". Berichte der Deutschen Chemischen Gesellschaft B. 64: 2167–2171. doi:10.1002/cber.19310640849.
- ^ Batta, Ashok K.; Xu, Guorong; Honda, Akira; Miyazaki, Teruo; Salen, Gerald (2006). "Stigmasterol reduces plasma cholesterol levels and inhibits hepatic synthesis and intestinal absorption in the rat". Metabolism: Clinical and Experimental. 55 (3): 292–299. doi:10.1016/j.metabol.2005.08.024. PMID 16483871.
- ^ Heinemann T, Pietruck B, Kullak-Ublick G, von Bergmann K (1988). "Comparison of sitosterol and sitostanol on inhibition of intestinal cholesterol absorption". Agents and Actions. Supplements. 26: 117–122. PMID 3265272.
- ^ Heinemann T, Kullak-Ublick GA, Pietruck B, von Bergmann K (1991). "Mechanisms of action of plant sterols on inhibition of cholesterol absorption. Comparison of sitosterol and sitostanol". European Journal of Clinical Pharmacology. 40 (Suppl 1): S59–63. doi:10.1007/BF01409411. PMID 2044646. S2CID 23279253.
- ^ Thomasson Crompton, David William; Nickol, Brent B. (1985). Biology of the Acanthocephala. Cambridge University Press. hlm. 185. ISBN 9780521246743.
- ^ Paxena, P. B. (2007). Chemistry of Alkaloids. Discovery Publishing Hous. hlm. 231. ISBN 9788183563161.
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