Turmerona
Turmerona adalah sekelompok senyawa kimia terkait dari kelas seskuiterpena. Senyawa ini ditemukan dalam kunyit (Curcuma longa),[1] yang menjadi asal namanya, serta tumbuhan terkait lainnya seperti Curcuma caesia.[2] Terdapat beberapa tipe struktur turmerona yang berbeda dalam jumlah dan penempatan ikatan ganda, termasuk α-turmerona, β-turmerona (juga dikenal sebagai kurlona), dan ar-turmerona. Masing-masing tipe ini terdiri dari beberapa stereoisomer.
Sejumlah aktivitas biologis in vitro dari turmerona telah dilaporkan termasuk aktivitas antiinflamasi, imunomodulator, antiproliferatif, dan antijamur.[3][4][5]
Contoh struktur kimia
 α-turmerona
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 β-turmerona
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 ar-turmerona
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-turmerone.svg) (S)-turmerona
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-alpha-turmerone.svg) (S)-α-turmerona
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-beta-turmerone.svg) (+)-β-turmerona
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-ar-turmerone.svg) (S)-ar-turmerona
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Referensi
- ^ Xiang, Hongping; Zhang, Lanyue; Xi, Lu; Yang, Yan; Wang, Xiaowei; Lei, Dehua; Zheng, Xi; Liu, Xiaoxuan (2018). "Phytochemical profiles and bioactivities of essential oils extracted from seven Curcuma herbs". Industrial Crops and Products. 111: 298–305. doi:10.1016/j.indcrop.2017.10.035.
- ^ Dosoky, Noura; Setzer, William (2018). "Chemical Composition and Biological Activities of Essential Oils of Curcuma Species". Nutrients. 10 (9): 1196. doi:10.3390/nu10091196. PMC 6164907. PMID 30200410.
- ^ Takemoto, Yuki; Kishi, Chihiro; Ehira, Hinano; Matsui, Nobutaka; Yamaguchi, Taichi; Yoshioka, Yuri; Matsumura, Shinichi; Moriyama, Tatsuya; Zaima, Nobuhiro (2022). "Inhaled turmerones can be incorporated in the organs via pathways different from oral administration and can affect weight-gain of mice". Scientific Reports. 12 (1): 11039. Bibcode:2022NatSR..1211039T. doi:10.1038/s41598-022-15168-9. PMC 9247068. PMID 35773461.
- ^ Obulesu, Magisetty (2021). "Health benefits of turmeric: Emphasis on anticancer activity". Turmeric and Curcumin for Neurodegenerative Diseases. hlm. 3–18. doi:10.1016/B978-0-12-822448-9.00006-6. ISBN 9780128224489. S2CID 234175081.
- ^ Kuttan, Ramadasan; Liju, Vijayastelterb; Jeena, Kottarapat (2011). "An evaluation of antioxidant, anti-inflammatory, and antinociceptive activities of essential oil from Curcuma longa. L". Indian Journal of Pharmacology. 43 (5): 526–531. doi:10.4103/0253-7613.84961. PMC 3195121. PMID 22021994.
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