Konektomika
Konektomika je proizvodnja konektoma i istovremeno i nauka o konektomimima: sveobuhvatnoj mapi neuronskih mreža unutar nervnog sistema organizama, tipski mozga ili oka. Pošto su ove strukture izuzetno složene, metodi u ovoj oblasti koristite visoko-propusnu primjenu neuronskih slika i histološkie tehnike, kako bi se povećala brzina, efikasnost i rješavanje mape mnoštva neuronskih veze u nervnom sistemu. Iako je mozak u glavnom fokusu takvog projekta, konektomika može teorijski mapirati bilo koje neuronske veze, uključujući, npr nervno-mišićne veze
Alati
Jedan od glavnih alata koji se koriste za istraživanja u konektomici na makro razini je MRI difuzija. Da biste vidjeli jedan od prvih mikro-konektoma u punoj rezoluciji, posjetite Open Connectome Project, koja je domaćin nekoliko konektom setova podataka, uključujući i 12TB skup od Bock et al. (2011.).[1]
Glavni alat u konektomici za istraživanja na mikroskali 3D je elektronska microskopija.[2]
Također pogledajte
Reference
- ^ Wedeen, V.J.; Wang, R.P.; Schmahmann, J.D.; Benner, T.; Tseng, W.Y.I.; Dai, G.; Pandya, D.N.; Hagmann, P.; et al. (2008). "Diffusion spectrum magnetic resonance imaging (DSI) tractography of crossing fibers". NeuroImage. 41 (4): 1267–77. doi:10.1016/j.neuroimage.2008.03.036. PMID 18495497.
- ^ Anderson, JR; Jones, BW; Watt, CB; Shaw, MV; Yang, JH; Demill, D; Lauritzen, JS; Lin, Y; et al. (2011). "Exploring the retinal connectome". Molecular vision. 17: 355–79. PMC 3036568. PMID 21311605.
Vanjski linkovi
- Open Connectome Project
- The Connectome Project at Harvard
- Connectome Research by EPFL/CHUV, Lausanne, Switzerland
- The NIH Blueprint for Neuroscience Research
- "I am my connectome".
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