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MIS18A

MIS18A
Identifikatori
AliasiMIS18A
Vanjski ID-jeviOMIM: 618137 MGI: 1913828 HomoloGene: 41294 GeneCards: MIS18A
Lokacija gena (čovjek)
Hromosom 21 (čovjek)
Hrom.Hromosom 21 (čovjek)[1]
Hromosom 21 (čovjek)
Genomska lokacija za MIS18A
Genomska lokacija za MIS18A
Bend21q22.11Početak32,268,228 bp[1]
Kraj32,279,049 bp[1]
Lokacija gena (miš)
Hromosom 16 (miš)
Hrom.Hromosom 16 (miš)[2]
Hromosom 16 (miš)
Genomska lokacija za MIS18A
Genomska lokacija za MIS18A
Bend16|16 C3.3Početak90,516,200 bp[2]
Kraj90,524,292 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0001948, GO:0016582 vezivanje za proteine
vezivanje iona metala
Ćelijska komponenta hromosom
nukleoplazma
Primarno suženje
jedro
Hromatin
citosol
Biološki proces Ćelijska dioba
regulation of DNA methylation
ćelijski ciklus
hromosomska segregacija
GO:0061641 CENP-A containing chromatin assembly
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_018944

NM_025642

RefSeq (bjelančevina)

NP_061817

NP_079918

Lokacija (UCSC)Chr 21: 32.27 – 32.28 MbChr 16: 90.52 – 90.52 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Protein Mis18-alfa jest protein koji je kod ljudi kodiran genom MIS18A sa hromosoma 21.[5][6]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 233 aminokiseline, a molekulska težina 25.863 Da.[6]

1020304050
MAGVRSLRCSRGCAGGCECGDKGKCSDSSLLGKRLSEDSSRHQLLQKWAS
MWSSMSEDASVADMERAQLEEEAAAAEERPLVFLCSGCRRPLGDSLSWVA
SQEDTNCILLRCVSCNVSVDKEQKLSKREKENGCVLETLCCAGCSLNLGY
VYRCTPKNLDYKRDLFCLSVEAIESYVLGSSEKQIVSEDKELFNLESRVE
IEKSLTQMEDVLKALQMKLWEAESKLSFATCKS

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000159055 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022978 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Fujita Y, Hayashi T, Kiyomitsu T, Toyoda Y, Kokubu A, Obuse C, Yanagida M (Jan 2007). "Priming of centromere for CENP-A recruitment by human hMis18alpha, hMis18beta, and M18BP1". Developmental Cell. 12 (1): 17–30. doi:10.1016/j.devcel.2006.11.002. PMID 17199038.
  6. ^ a b "Entrez Gene: C21orf45 chromosome 21 open reading frame 45".

Dopunska literatura

Vanjski linkovi

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