NOB1
| NOB1 | |||||||||||||||||||||||||
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| Identifikatori | |||||||||||||||||||||||||
| Aliasi | NOB1 | ||||||||||||||||||||||||
| Vanjski ID-jevi | OMIM: 613586 MGI: 1914869 HomoloGene: 31924 GeneCards: NOB1 | ||||||||||||||||||||||||
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| Ortolozi | |||||||||||||||||||||||||
| Vrste | Čovjek | Miš | |||||||||||||||||||||||
| Entrez | |||||||||||||||||||||||||
| Ensembl | |||||||||||||||||||||||||
| UniProt | |||||||||||||||||||||||||
| RefSeq (mRNK) | |||||||||||||||||||||||||
| RefSeq (bjelančevina) | |||||||||||||||||||||||||
| Lokacija (UCSC) | Chr 16: 69.74 – 69.75 Mb | Chr 8: 108.14 – 108.15 Mb | |||||||||||||||||||||||
| PubMed pretraga | [3] | [4] | |||||||||||||||||||||||
| Wikipodaci | |||||||||||||||||||||||||
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RNK-vezujući protein NOB1 je protein koji je kod ljudi kodiran genom NOB1.[5][6]
Hartz (2010) je mapirala gen NOB1 u hromosomu, regija 16q22.1, na osnovu poravnanja sekvence NOB1 (GenBank AB026125) sa genomskom sekvencom (GRCh37).
Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 412 aminokiselina, a molekulska težina 46.675 Da[7].
- Simboli
C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MAPVEHVVAD | AGAFLRHAAL | QDIGKNIYTI | REVVTEIRDK | ATRRRLAVLP | ||||
| YELRFKEPLP | EYVRLVTEFS | KKTGDYPSLS | ATDIQVLALT | YQLEAEFVGV | ||||
| SHLKQEPQKV | KVSSSIQHPE | TPLHISGFHL | PYKPKPPQET | EKGHSACEPE | ||||
| NLEFSSFMFW | RNPLPNIDHE | LQELLIDRGE | DVPSEEEEEE | ENGFEDRKDD | ||||
| SDDDGGGWIT | PSNIKQIQQE | LEQCDVPEDV | RVGCLTTDFA | MQNVLLQMGL | ||||
| HVLAVNGMLI | REARSYILRC | HGCFKTTSDM | SRVFCSHCGN | KTLKKVSVTV | ||||
| SDDGTLHMHF | SRNPKVLNPR | GLRYSLPTPK | GGKYAINPHL | TEDQRFPQLR | ||||
| LSQKARQKTN | VFAPDYIAGV | SPFVENDISS | RSATLQVRDS | TLGAGRRRLN | ||||
| PNASRKKFVK | KR |
Reference
- ^ a b c GRCh38: Ensembl release 89: ENSG00000141101 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000003848 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Zhang Y, Ni J, Zhou G, Yuan J, Ren W, Shan Y, Tang W, Yu L, Zhao S (Sep 2005). "Cloning, expression and characterization of the human NOB1 gene". Mol Biol Rep. 32 (3): 185–9. doi:10.1007/s11033-005-3141-7. PMID 16172919. S2CID 12892523.
- ^ "Entrez Gene: NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)".
- ^ "UniProt, Q9ULX3". Pristupljeno 8. 7. 2021.
Dopunska literatura
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Fatica A, Oeffinger M, Dlakić M, Tollervey D (2003). "Nob1p is required for cleavage of the 3' end of 18S rRNA". Mol. Cell. Biol. 23 (5): 1798–807. doi:10.1128/MCB.23.5.1798-1807.2003. PMC 151717. PMID 12588997.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Daniele A, Altruda F, Ferrone M, et al. (1992). "Cloning and expression of a new human polypeptide which regulates protein phosphorylation in Escherichia coli". Mol. Cell. Biochem. 107 (2): 87–94. doi:10.1007/bf00225511. PMID 1791827. S2CID 25617287.
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