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NOC2L

NOC2L
Identifikatori
AliasiNOC2L
Vanjski ID-jeviOMIM: 610770 MGI: 1931051 HomoloGene: 6980 GeneCards: NOC2L
Lokacija gena (čovjek)
Hromosom 1 (čovjek)
Hrom.Hromosom 1 (čovjek)[1]
Hromosom 1 (čovjek)
Genomska lokacija za NOC2L
Genomska lokacija za NOC2L
Bend1p36.33Početak944,203 bp[1]
Kraj959,309 bp[1]
Lokacija gena (miš)
Hromosom 4 (miš)
Hrom.Hromosom 4 (miš)[2]
Hromosom 4 (miš)
Genomska lokacija za NOC2L
Genomska lokacija za NOC2L
Bend4|4 E2Početak156,320,376 bp[2]
Kraj156,332,073 bp[2]
Obrazac RNK ekspresije
Više referentnih podataka o ekspresiji
Ontologija gena
Molekularna funkcija GO:0031493 histone binding
nucleosome binding
chromatin binding
GO:0001948, GO:0016582 vezivanje za proteine
GO:0001106 transcription corepressor activity
vezivanje sa RNK
Ćelijska komponenta Noc1p-Noc2p complex
Noc2p-Noc3p complex
Jedarce
jedro
nukleoplazma
citosol
Biološki proces cellular response to UV
negative regulation of B cell apoptotic process
negative regulation of histone acetylation
GO:1901227 negative regulation of transcription by RNA polymerase II
GO:0009373 regulation of transcription, DNA-templated
transcription, DNA-templated
negative regulation of intrinsic apoptotic signaling pathway
GO:0097285 apoptoza
ribosomal large subunit biogenesis
regulation of signal transduction by p53 class mediator
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_015658

NM_021303
NM_001369270

RefSeq (bjelančevina)

NP_056473

n/a

Lokacija (UCSC)Chr 1: 0.94 – 0.96 MbChr 4: 156.32 – 156.33 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Homolog jedarcetovog kompleksa proteina 2 jest protein koji je kod ljudi kodiran genom NOC2L sa hromosoma 1.[5]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 749 aminokiselina, a molekulska težina 84.919 Da.[6]

1020304050
MAAAGSRKRRLAELTVDEFLASGFDSESESESENSPQAETREAREAARSP
DKPGGSPSASRRKGRASEHKDQLSRLKDRDPEFYKFLQENDQSLLNFSDS
DSSEEEEGPFHSLPDVLEEASEEEDGAEEGEDGDRVPRGLKGKKNSVPVT
VAMVERWKQAAKQRLTPKLFHEVVQAFRAAVATTRGDQESAEANKFQVTD
SAAFNALVTFCIRDLIGCLQKLLFGKVAKDSSRMLQPSSSPLWGKLRVDI
KAYLGSAIQLVSCLSETTVLAAVLRHISVLVPCFLTFPKQCRMLLKRMVI
VWSTGEESLRVLAFLVLSRVCRHKKDTFLGPVLKQMYITYVRNCKFTSPG
ALPFISFMQWTLTELLALEPGVAYQHAFLYIRQLAIHLRNAMTTRKKETY
QSVYNWQYVHCLFLWCRVLSTAGPSEALQPLVYPLAQVIIGCIKLIPTAR
FYPLRMHCIRALTLLSGSSGAFIPVLPFILEMFQQVDFNRKPGRMSSKPI
NFSVILKLSNVNLQEKAYRDGLVEQLYDLTLEYLHSQAHCIGFPELVLPV
VLQLKSFLRECKVANYCRQVQQLLGKVQENSAYICSRRQRVSFGVSEQQA
VEAWEKLTREEGTPLTLYYSHWRKLRDREIQLEISGKERLEDLNFPEIKR
RKMADRKDEDRKQFKDLFDLNSSEEDDTEGFSERGILRPLSTRHGVEDDE
EDEEEGEEDSSNSEDGDPDAEAGLAPGELQQLAQGPEDELEDLQLSEDD

Reference

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000188976 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000095567 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)".
  6. ^ "UniProt, Q9Y3T9" (jezik: engleski). Pristupljeno 14. 12. 2021.

Dopunska literatura

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