SCRN1
| SCRN1 | |||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||||||||||||||||||
| Aliasi | SCRN1 | ||||||||||||||||||||||||
| Vanjski ID-jevi | OMIM: 614965 MGI: 1917188 HomoloGene: 8853 GeneCards: SCRN1 | ||||||||||||||||||||||||
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| Ortolozi | |||||||||||||||||||||||||
| Vrste | Čovjek | Miš | |||||||||||||||||||||||
| Entrez | |||||||||||||||||||||||||
| Ensembl | |||||||||||||||||||||||||
| UniProt | |||||||||||||||||||||||||
| RefSeq (mRNK) | |||||||||||||||||||||||||
| RefSeq (bjelančevina) | |||||||||||||||||||||||||
| Lokacija (UCSC) | Chr 7: 29.92 – 29.99 Mb | Chr 6: 54.48 – 54.54 Mb | |||||||||||||||||||||||
| PubMed pretraga | [3] | [4] | |||||||||||||||||||||||
| Wikipodaci | |||||||||||||||||||||||||
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Sekernin-1 je protein koji je kod ljudi kodiran genom SCRN1.[5][6]
Aminokiselinska sekvenca
Dužina polipeptidnog lanca je 414 aminokiselina, а molekulska težina 46.382 Da.[7]
| 10 | 20 | 30 | 40 | 50 | ||||
|---|---|---|---|---|---|---|---|---|
| MAAAPPSYCF | VAFPPRAKDG | LVVFGKNSAR | PRDEVQEVVY | FSAADHEPES | ||||
| KVECTYISID | QVPRTYAIMI | SRPAWLWGAE | MGANEHGVCI | ANEAINTREP | ||||
| AAEIEALLGM | DLVRLGLERG | ETAKEALDVI | VSLLEEHGQG | GNYFEDANSC | ||||
| HSFQSAYLIV | DRDEAWVLET | IGKYWAAEKV | TEGVRCICSQ | LSLTTKMDAE | ||||
| HPELRSYAQS | QGWWTGEGEF | NFSEVFSPVE | DHLDCGAGKD | SLEKQEESIT | ||||
| VQTMMNTLRD | KASGVCIDSE | FFLTTASGVS | VLPQNRSSPC | IHYFTGTPDP | ||||
| SRSIFKPFIF | VDDVKLVPKT | QSPCFGDDDP | AKKEPRFQEK | PDRRHELYKA | ||||
| HEWARAIIES | DQEQGRKLRS | TMLELEKQGL | EAMEEILTSS | EPLDPAEVGD | ||||
| LFYDCVDTEI | KFFK |
Reference
- ^ a b c GRCh38: Ensembl release 89: ENSG00000136193 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019124 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Way G, Morrice N, Smythe C, O'Sullivan AJ (Sep 2002). "Purification and identification of secernin, a novel cytosolic protein that regulates exocytosis in mast cells" (PDF). Mol Biol Cell. 13 (9): 3344–54. doi:10.1091/mbc.E01-10-0094. PMC 124164. PMID 12221138.
- ^ "Entrez Gene: SCRN1 secernin 1".
- ^ "UniProt, Q12765" (jezik: engleski). Pristupljeno 27. 9. 2021.
Dopunska literatura
- Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
- Nagase T, Seki N, Ishikawa K, et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.
- Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
- Hoja MR, Wahlestedt C, Höög C (2000). "A visual intracellular classification strategy for uncharacterized human proteins". Exp. Cell Res. 259 (1): 239–46. doi:10.1006/excr.2000.4948. PMID 10942595.
- O'Neill EE, Brock CJ, von Kriegsheim AF, et al. (2002). "Towards complete analysis of the platelet proteome". Proteomics. 2 (3): 288–305. doi:10.1002/1615-9861(200203)2:3<288::AID-PROT288>3.0.CO;2-0. PMID 11921445.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Suda T, Tsunoda T, Uchida N, et al. (2006). "Identification of secernin 1 as a novel immunotherapy target for gastric cancer using the expression profiles of cDNA microarray". Cancer Sci. 97 (5): 411–9. doi:10.1111/j.1349-7006.2006.00194.x. PMID 16630140. S2CID 25739515.
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Index:
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