Staufen homolog 2 je član porodice proteina koji se vezuju za dvolančanu RNK (dsRNK), uključeni u transport i/ili lokalizaciju iRNK u različite podćelijske odjele i/ili organele. Ove proteine karakterizira prisutnost više dsRNK-vezujućih domena, koji su potrebni za vezanje RNK sa dvolančanom sekundarnom strukturom. Staufenski homolog 2 ima 48,5% i 59,9% sličnosti sa staufenom kod Drosophila i ljudi. Tačna funkcija staufen homologa 2 nije poznata, ali budući da sadrži tri kopije konzerviranog domena vezanja dsRNK, mogla bi biti uključena u događaje vezanja za dvolančane RNK.[6]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Buchner G, Bassi MT, Andolfi G, Ballabio A, Franco B (novembar 1999). "Identification of a novel homolog of the Drosophila staufen protein in the chromosome 8q13-q21.1 region". Genomics. 62 (1): 113–8. doi:10.1006/geno.1999.6015. PMID10585778.
Duchaîne TF, Hemraj I, Furic L, Deitinghoff A, Kiebler MA, DesGroseillers L (august 2002). "Staufen2 isoforms localize to the somatodendritic domain of neurons and interact with different organelles". Journal of Cell Science. 115 (Pt 16): 3285–95. PMID12140260.
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