ZNF268

ZNF268
Dostupne strukture
PDB	Pretraga Human UniProta: PDBe RCSB
Spisak PDB ID kodova
	2EL4, 2EL5, 2EL6, 2EM1, 2EMV, 2EMW, 2EMX, 2EMY, 2EN0, 2EN6, 2EN7, 2EOF, 2EOG, 2EOI, 2EOJ, 2EOK, 2EOL, 2EOP, 2EPV, 2EPW, 2EPY, 2YTF, 2YTQ
Identifikatori
Aliasi	ZNF268
Vanjski ID-jevi	OMIM: 604753 HomoloGene: 124392 GeneCards: ZNF268
Lokacija gena (čovjek)
Hrom.	Hromosom 12 (čovjek)
Kraj	133,214,832 bp
Ontologija gena
Molekularna funkcija	• nucleic acid binding; • vezivanje sa DNK; • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • vezivanje iona metala; • GO:0001948, GO:0016582 vezivanje za proteine; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Ćelijska komponenta	• intracellular anatomical structure; • citoplazma; • actin cytoskeleton; • jedro; • citosol;
Biološki proces	• GO:0009373 regulation of transcription, DNA-templated; • Ćelijska diferencijacija; • positive regulation of protein phosphorylation; • GO:1903364 positive regulation of protein catabolic process; • regulation of protein heterodimerization activity; • positive regulation of cell migration; • cellular response to tumor necrosis factor; • negative regulation of apoptotic process; • GO:1901227 negative regulation of transcription by RNA polymerase II; • positive regulation of protein homodimerization activity; • transcription, DNA-templated; • positive regulation of cell differentiation; • positive regulation of cell population proliferation; • regulation of mitotic cell cycle; • positive regulation of apoptotic process; • negative regulation of cell population proliferation; • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II; • positive regulation of NIK/NF-kappaB signaling;
	Izvori:Amigo / QuickGO
Ortolozi
	10795
	n/a
	ENSG00000090612
	n/a
	Q14587
	n/a
NM_152943; NM_001165881; NM_001165882; NM_001165883; NM_001165884;
	NM_001165885; NM_001165886; NM_001165887; NM_003415
	n/a
NP_001159353; NP_001159354; NP_001159355; NP_001159356; NP_001159357;
	NP_001159358; NP_001159359; NP_003406; NP_694422
	n/a
	Wikipodaci
Pogledaj/uredi – čovjek

Protein cinkovog prsta 268 je protein koji je kod ljudi kodiran genom ZNF268.^[3]^[4]

Aminokiselinska sekvenca

Dužina polipeptidnog lanca je 94 aminokiseline, a molekulska težina 11 068 Da.^[5]

Simboli

C: Cistein
D: Asparaginska kiselina
E: Glutaminska kiselina
F: Fenilalanin
G: Glicin
H: Histidin
I: Izoleucin
K: Lizin
L: Leucin
M: Metionin
N: Asparagin
P: Prolin
Q: Glutamin
R: Arginin
S: Serin
T: Treonin
V: Valin
W: Triptofan
Y: Tirozin

10		20		30		40		50
MDVFVDFTWE		EWQLLDPAQK		CLYRSVMLEN		YSNLVSLGYQ		HTKPDIIFKL
EQGEELCMVQ		AQVPNQTCPN		TVWKIDDLMD		WHQENKDKLG		STAK

Reference

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000090612 - Ensembl, maj 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Abrink M, Aveskogh M, Hellman L (Mar 1995). "Isolation of cDNA clones for 42 different Kruppel-related zinc finger proteins expressed in the human monoblast cell line U-937". DNA Cell Biol. 14 (2): 125–36. doi:10.1089/dna.1995.14.125. PMID 7865130.
^ "Entrez Gene: ZNF268 zinc finger protein 268".
^ "UniProt, K7EMS6". Pristupljeno 8. 8. 2021.