Isomerase
I biokemi er en isomerase et enzym, der katalyserer den strukturelle omdannelse af isomerer. Isomeraser katalyserer således reaktioner på formen
- A → B,
hvor A og B er hinandens isomerer.
Nomenklatur
Isomerasers navne dannes som "substratisomerase" (for eksempel glukose-6-fosfatisomerase), eller som "substrat-type af isomerase" (for eksempel fosfoglukomutase).
Klassifikation
Isomeraser har deres egne EC-numre i enzymklassifikationssystemet: EC 5. Isomeraser kan yderligere klassificeres i seks underklasser:
- EC 5.1 inkluderer enzymer, der katalyserer racemisering (racemaser) og epimerisering (epimeraser)
- EC 5.2 inkluderer enzymer, der katalyserer isomeriseringen af geometriske isomerer (cis-transisomeraser)
- EC 5.3 inkluderer intramolekylære oxidoreduktaser
- EC 5.4 inkluderer intramolekylære transferaser (mutaser)
- EC 5.5 inkluderer intramolekylære lyaser
- EC 5.99 inkluderer andre isomeraser (inklusiv topoisomeraser)
Referencer
- EC 5-introduktion fra Afdelingen for Kemi ved Queen Mary, University of London
Eksterne henvisninger
- GoPubMed: Top authors, journals, places publishing on Isomerases Arkiveret 21. februar 2009 hos Wayback Machine
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