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Sertralin

3D-model af setralin-molekyle

Sertralin (Udgivet under navnet Zoloft, Lustral , Selektra og andre) er et antidepressivum af klassen selektive serotoningenoptagshæmmere (SSRI). Det blev først introduceret på markedet af Pfizer i 1991. Sertralin anvendes til behandling af depression. Midlet anvendes desuden ved angst for samvær med andre (socialfobi), panikangst, stress efter ulykker eller lign. voldsomme hændelser (posttraumatisk stresstilstand (PTSD)) samt tvangsforestillinger og -handlinger (obsessiv-kompulsiv tilstand (OCD)).[1] Den maksimale døgndosis for Sertralin er normalvis 200mg for alle indikationer nævnt ovenfor, men kan undtagelsesvist bruges i doser op til 400mg mod OCD i tilfælde af manglende effekt.[2]

I 2013 var sertralin det mest ordinerede antidepressivum og næstmest ordinerede psykofarmaka (efter Alprazolam) på det amerikanske marked med over 41 millioner recepter.[3]

Referencer

  1. ^ "SSRI-præparater". min.medicin.dk. Hentet 30. maj 2018.
  2. ^ https://pro.medicin.dk/Medicin/Praeparater/3304#a100
  3. ^ John M. Grohol (2014). "Top 25 Psychiatric Medication Prescriptions for 2013". Psych Central. Arkiveret fra originalen 31. marts 2015. Hentet 3. april 2015.

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