The 2004–05 Maltese First Division (known as the MIA First Division for sponsorship reasons) started on 5 September 2004 and finished on 15 May 2005.
Ħamrun Spartans were promoted back to the Premier League after just one season away, following their relegation alongside Balzan Youths in the 2003–04 Premier League season. Mosta joined Ħamrun in securing place in the Premier League. Balzan suffered a consecutive relegation, and alongside Gozo were relegated to the 2005–06 Second Division.
Source: [2] Legend: Blue = home team win; Yellow = draw; Red = away team win. Notes:
^The match between St. George's and Senglea Athletic was abandoned at the 77th minute with the result 1–2 in favour of Senglea Athletic after a fan attacked a linesman. The match was awarded to Senglea Athletic with a 2–0 score.