Ashleigh Barty defeated Jil Teichmann in the final, 6–3, 6–1 to win the women's singles tennis title at the 2021 Cincinnati Masters. Barty did not drop a set en route to her first Cincinnati Masters title.[1] It was her fifth and last title of the season, her third WTA 1000 title, and her 13th career WTA Tour singles title.[2]
Victoria Azarenka was the defending champion, but lost in the third round to Barty.[3]
Angelique Kerber contested her 1000th match in her professional career in the quarterfinals against Petra Kvitová; she won the match after Kvitová retired.[citation needed]
This was the final tournament in which former world No. 4 and British No. 1 Johanna Konta competed before her retirement. She was defeated in the first round by Karolína Muchová.
Seeds
The top eight seeds received a bye into the second round.
Bold denotes the mandatory tournaments (WTA 1000) † – Tournaments are affected by the COVID-19 pandemic * – Tournaments are introduced due to the impact of the COVID-19 pandemic