Bat SARS-like coronavirus WIV1 Species of virus
Bat SARS-like coronavirus WIV1 (Bat SL-CoV-WIV1 ), also sometimes called SARS-like coronavirus WIV1 , is a strain of severe acute respiratory syndrome–related coronavirus (SARSr-CoV) isolated from Chinese rufous horseshoe bats in 2013 (Rhinolophus sinicus ).[ 1] [ 2] Like all coronaviruses, virions consist of single-stranded positive-sense RNA enclosed within an envelope .[ 3]
WIV1 was named for the Wuhan Institute of Virology , where it was discovered by a researcher on Shi Zhengli 's team.[ 4]
Zoonosis
The discovery confirms that bats are the natural reservoir of SARS-CoV. Phylogenetic analysis shows the possibility of direct transmission of SARS from bats to humans without the intermediary Chinese civets , as previously believed.[ 5]
Phylogenetic
A phylogenetic tree based on whole-genome sequences of SARS-CoV-1 and related coronaviruses is:
See also
References
^ Xing-Yi Ge; Jia-Lu Li; Xing-Lou Yang; et al. (2013). "Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor" . Nature . 503 (7477): 535– 8. Bibcode :2013Natur.503..535G . doi :10.1038/nature12711 . PMC 5389864 . PMID 24172901 .
^ "Taxonomy: Bat SARS-like coronavirus WIV1" . www.ncbi.nlm.nih.gov . Retrieved 2020-02-20 .
^ Naik, Gautam (2013-10-30). "Study: Bat-to-Human Leap Likely for SARS-Like Virus - WSJ.com" . Wall Street Journal . Online.wsj.com. Retrieved 2013-10-31 .
^ Qiu, Jane. "Meet the scientist at the center of the covid lab leak controversy" . MIT Technology Review . Archived from the original on 2022-02-14. Retrieved 2024-06-03 .
^ Vineet D. Menachery et al. , SARS-like WIV1-CoV poised for human emergence, 2016. doi :10.1073/pnas.1517719113
^ Kim, Yongkwan; Son, Kidong; Kim, Young-Sik; Lee, Sook-Young; Jheong, Weonhwa; Oem, Jae-Ku (2019). "Complete genome analysis of a SARS-like bat coronavirus identified in the Republic of Korea" . Virus Genes . 55 (4): 545– 549. doi :10.1007/s11262-019-01668-w . PMC 7089380 . PMID 31076983 .
^ Xu, L; Zhang, F; Yang, W; Jiang, T; Lu, G; He, B; Li, X; Hu, T; Chen, G; Feng, Y; Zhang, Y; Fan, Q; Feng, J; Zhang, H; Tu, C (February 2016). "Detection and characterization of diverse alpha- and betacoronaviruses from bats in China" . Virologica Sinica . 31 (1): 69– 77. doi :10.1007/s12250-016-3727-3 . PMC 7090707 . PMID 26847648 .
^ a b Li, W. (2005). "Bats Are Natural Reservoirs of SARS-Like Coronaviruses" . Science . 310 (5748): 676– 679. Bibcode :2005Sci...310..676L . doi :10.1126/science.1118391 . ISSN 0036-8075 . PMID 16195424 . S2CID 2971923 .
^ a b Xing‐Yi Ge; Ben Hu; Zheng‐Li Shi (2015). "BAT CORONAVIRUSES". In Lin-Fa Wang; Christopher Cowled (eds.). Bats and Viruses: A New Frontier of Emerging Infectious Diseases (First ed.). John Wiley & Sons. pp. 127– 155. doi :10.1002/9781118818824.ch5 .
^ He, Biao; Zhang, Yuzhen; Xu, Lin; Yang, Weihong; Yang, Fanli; Feng, Yun; et al. (2014). "Identification of diverse alphacoronaviruses and genomic characterization of a novel severe acute respiratory syndrome-like coronavirus from bats in China" . J Virol . 88 (12): 7070– 82. doi :10.1128/JVI.00631-14 . PMC 4054348 . PMID 24719429 .
^ a b Lau, Susanna K. P.; Feng, Yun; Chen, Honglin; Luk, Hayes K. H.; Yang, Wei-Hong; Li, Kenneth S. M.; Zhang, Yu-Zhen; Huang, Yi; et al. (2015). "Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination" . Journal of Virology . 89 (20): 10532– 10547. doi :10.1128/JVI.01048-15 . ISSN 0022-538X . PMC 4580176 . PMID 26269185 .
^ a b Xing-Yi Ge; Jia-Lu Li; Xing-Lou Yang; et al. (2013). "Isolation and characterization of a bat SARS-like coronavirus that uses the ACE2 receptor" . Nature . 503 (7477): 535– 8. Bibcode :2013Natur.503..535G . doi :10.1038/nature12711 . PMC 5389864 . PMID 24172901 .
^ Yang, Xing-Lou; Hu, Ben; Wang, Bo; Wang, Mei-Niang; Zhang, Qian; Zhang, Wei; et al. (2016). "Isolation and Characterization of a Novel Bat Coronavirus Closely Related to the Direct Progenitor of Severe Acute Respiratory Syndrome Coronavirus" . Journal of Virology . 90 (6): 3253– 6. doi :10.1128/JVI.02582-15 . PMC 4810638 . PMID 26719272 .
^ Ben, Hu; Hua, Guo; Peng, Zhou; Zheng-Li, Shi (2020). "Characteristics of SARS-CoV-2 and COVID-19" . Nature Reviews Microbiology . 19 (3): 141– 154. doi :10.1038/s41579-020-00459-7 . PMC 7537588 . PMID 33024307 .
Bat SARS-like coronavirus WIV1