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Eosin Y

Eosin Y
Names
IUPAC name
2-(2,4,5,7-tetrabromo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate [in its deprotonated form]
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.037.629 Edit this at Wikidata
MeSH Eosine+Yellowish-(YS)
UNII
  • InChI=1S/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2 checkY
    Key: SEACYXSIPDVVMV-UHFFFAOYSA-L checkY
  • InChI=1/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2
    Key: SEACYXSIPDVVMV-NUQVWONBAJ
  • c1ccc(c(c1)c2c3cc(c(c(c3oc-4c(c(=O)c(cc24)Br)Br)Br)[O-])Br)C(=O)[O-].[Na+].[Na+]
Properties
C20H6Br4Na2O5
Molar mass 647.89052
Appearance Red powder
Density 1.018 g·cm−3
Melting point 295.5 °C (563.9 °F; 568.6 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Eosin Y, also called C.I. 45380[1][2] or C.I. Acid Red 87,[2][1] is a member of the triarylmethane dyes. It is produced from fluorescein by bromination.[3]

Use

Eosin Y is commonly used as the red dye in red inks.

It is commonly used in histology, most notably in the H&E (Haematoxylin and Eosin) stain.[1] Eosin Y is also widely used in the Papanicolaou stain (or Pap stain used in the Pap test) and the Romanowsky type cytologic stains.[1][2] It is also used as a photosensitizer in organic synthesis.[4]

  • Eosin Y solution for staining microscopy slides.
    Eosin Y solution for staining microscopy slides.
  • Eosinophilic staining, using eosin Y, compared to other patterns when using hematoxylin and eosin (H&E).
    Eosinophilic staining, using eosin Y, compared to other patterns when using hematoxylin and eosin (H&E).

See also

References

  1. ^ a b c d Bancroft, John; Stevens, Alan, eds. (1982). The Theory and Practice of Histological Techniques (2nd ed.). Longman Group Limited.
  2. ^ a b c Lillie, Ralph Dougall (1977). H. J. Conn's Biological stains (9th ed.). Baltimore: Williams & Wilkins. pp. 692p.
  3. ^ Gessner, Thomas; Mayer, Udo (2000). "Triarylmethane and Diarylmethane Dyes". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a27_179. ISBN 978-3527306732.
  4. ^ Diercxsens, Nicolas (2017-04-10), "Eosin Y", Encyclopedia of Reagents for Organic Synthesis, Chichester, UK: John Wiley & Sons, Ltd, pp. 1–3, doi:10.1002/047084289x.rn02033, ISBN 978-0-470-84289-8


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