Fenoverine

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Fenoverine

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	A03AX05 (WHO)
Identifiers
IUPAC name 2-[4-(Benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-yl]-1-(10H-phenothiazin-10-yl)ethanone
CAS Number	37561-27-6
PubChem CID	72098
ChemSpider	65083
UNII	N274ZQ6PZJ
KEGG	D07095 Y
ChEMBL	ChEMBL1512949
CompTox Dashboard (EPA)	DTXSID8046296
ECHA InfoCard	100.048.666
Chemical and physical data
Formula	C26H15N3O3S
Molar mass	449.48 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN(CCN1CC2=CC3=C(C=C2)OCO3)CC(=O)N4C5=CC=CC=C5SC6=CC=CC=C64
InChI InChI=1S/C26H25N3O3S/c30-26(29-20-5-1-3-7-24(20)33-25-8-4-2-6-21(25)29)17-28-13-11-27(12-14-28)16-19-9-10-22-23(15-19)32-18-31-22/h1-10,15H,11-14,16-18H2 Key:UBAJTZKNDCEGKL-UHFFFAOYSA-N
(verify)

Fenoverine (INN) is an antispasmodic [also known as spasmolytics] drug,^[1] which acts by inhibiting calcium channels^[2] [much in the same way as traditional calcium channel blockers, which are used as antianginal drugs]. In the case of Fenoverine, the relaxation occurs in abdominal / intestinal smooth muscles, while in case of antianginal drugs, the relaxation occurs in coronary vessels. Notably Fenoverine does not act as an antianginal agent.

Fenoverine is known to cause rhabdomyolysis.^[2][3]

This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by expanding it.

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