Beginning in 1993, Grieder joined the faculty and conducted research at the medical school of the Uniformed Services University of the Health Sciences (USU) within the Department of Microbiology and Immunology, and Molecular/Cell Biology and Neuroscience in Bethesda, Maryland.[1][2] Her areas of expertise include viral-induced neuroimmunology and neurodegeneration, emerging viral threats and the molecular genetics of the VEE virus. In 2000, at the National Center for Research Resources (NCRR), Grieder began managing the Division of Comparative Medicine's Laboratory Animal Sciences Program, where she created the Mutant Mouse Regional Resource Centers Program and supervised grants related to mammalian models, comparative and functional genomics, and training opportunities for veterinarians and veterinary students. Grieder joined the National Institutes of Health (NIH) in 2000 as a program official in the Division of Comparative Medicine, which was located in the former National Center for Research Resources (NCRR). She was appointed director of the division in 2004, with responsibilities that include the management and oversight of the eight national primate research centers, primate breeding and resource-related projects, development of mammalian and non-mammalian animal model resources, pre- and post-doctoral training for veterinarians, and a variety of research projects.[3] From July 2012 to January 2013, Grieder served as the acting director of the Office of Research Infrastructure Programs (ORIP). She became the director of ORIP on January 13, 2013. She continues to serve as an adjunct faculty in the Department of Pathology and Program of Neuroscience at USU. At USU, her research focused on viral pathogenesis using mouse models to investigate neuroimmune mechanisms.[2]
She has written numerous articles and book chapters for scientific publications, and her research has appeared in peer-reviewed journals including Virology, Journal of Immunology and Nature Genetics.[1]
Austin, C. P.; Battey, J. F.; Bradley, A.; Bucan, M.; Capecchi, M.; Collins, F. S.; Dove, W. F.; Duyk, G.; Dymecki, S.; Eppig, J. T.; Grieder, F. B.; Heintz, N.; Hicks, G.; Insel, T. R.; Joyner, A.; Koller, B. H.; Lloyd, K. C.; Magnuson, T.; Moore, M. W.; Nagy, A.; Pollock, J. D.; Roses, A. D.; Sands, A. T.; Seed, B.; Skarnes, W. C.; Snoddy, J.; Soriano, P.; Stewart, D. J.; Stewart, F.; et al. (2004). "The Knockout Mouse Project". Nature Genetics. 36 (9): 921–924. doi:10.1038/ng0904-921. ISSN1061-4036. PMC2716027. PMID15340423.