After the 1987 season, Pettis went on to play two seasons with the Detroit Tigers, 1988 through the following season of 1989. After two years with Detroit, Pettis joined the Texas Rangers for two seasons, 1990–91. Pettis finished his career in the major leagues in 1992. The 1992 season saw Pettis play for two teams. After leaving the Texas Rangers, Pettis joined the San Diego Padres for the 1992 season but ended that season back in Detroit with the Tigers.
During his career, Pettis consistently hit for low averages and was known for striking out often, but he performed extremely well on defense, earning five Gold Glove Awards. He was noted for making many spectacular leaping or diving catches, depriving hitters of home runs or base hits, and was known in baseball circles as "The man who made center field look easy". Additionally, he was a prolific base runner and had five seasons where he stole over 40 bases. Pettis held the Angels' club record for stolen bases for nearly 20 years, until it was broken by Chone Figgins on July 15, 2007. Pettis was tagged as "Pac Man" Pettis by a local radio station listener call-in contest in 1986, referring to his unusual speed in the outfield and ability to chase down opponents' hits.
On his 1985 Topps baseball card, the person posing in the picture is not Pettis; it is in fact a picture of his younger brother, Lynn.[1]
In 2022, the Astros won 106 games, the second-highest total in franchise history. They advanced to the World Series and defeated the Philadelphia Phillies in six games to give Pettis his second World Series title as an Astro.[2] After the 2024 season, it was announced that the Astros would not renew Pettis' contract for the 2025 season, ending his tenure with the club.[3]