Supervillain name
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Notable alter ego
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First appearance issue #
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Creator
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Notes
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Mole Man and his Moloids
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Harvey Rupert Elder
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Fantastic Four No. 1 (November 1961)
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Stan Lee Jack Kirby
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An underground leader of Subterranea, who plans to take over the outer world that rejected him. Rules over different creatures and has access to highly advanced technology.
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Skrulls
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Various
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Fantastic Four No. 2 (January 1962)
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Stan Lee Jack Kirby
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An alien race that can shapeshift and are bent on taking over the Earth.
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Miracle Man
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Joshua Ayers
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Fantastic Four No. 3 (March 1962)
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Stan Lee Jack Kirby
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A magician with megalomaniacal goals.
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Namor the Sub-Mariner
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Namor McKenzie
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Fantastic Four No. 4 (May 1962)
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Bill Everett
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An underwater antihero who tried to win Invisible Woman's heart. He is the King of Atlantis. Originally the character was created for the Invaders for Timely Comics, and was reintroduced into Marvel Comics in 1962.
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Doctor Doom
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Victor von Doom
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Fantastic Four No. 5 (July 1962)
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Stan Lee Jack Kirby
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The Fantastic Four's deadliest archenemy. Ruler of Latveria, bent on dominating the Earth. A skilled sorcerer and one of the smartest people on Earth 616. Met Reed Richards and Ben Grimm while at college at the fictional Empire State University. He was permanently disfigured after an accident in which he tried contacting his deceased mother from beyond the grave. This disfigurement was only made worse when he prematurely put on his iconic mask before it was cool. One of Marvel's biggest and most popular villains.
While typically an enemy of the Fantastic Four, he has been known to help them, such as with the birth of Valeria Richards.[2]
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Kurrgo
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Kurrgo
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Fantastic Four No. 7 (July 1962)
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Stan Lee Jack Kirby
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A Xantha who is the dictator of the planet Xanth and master of its technology that is more advanced than Earth's technology. He had his robot bring the Fantastic Four to Xantha to help save his kind from an asteroid that will destroy Xanth. When Mister Fantastic came up with a way to shrink the Xanthas with a special gas in order to save them and relocate them to another planet by enlarging them, Kurrgo still plotted to rule his kind. Though he was thought to have perished in Xanth's destruction, Marvel Feature #11 revealed that Kurrgo's robot saved him and took him to a hidden spaceship which they used to escape Xanth's destruction. In order to regain control of the Xantha who have settled on New Xanth and repelled him with their technology, Kurrgo and his robot went to Earth to plan to use Thing in overcoming the Xantha only to end up competing against Leader after discovering that Hulk was stronger than Thing.
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Puppet Master
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Phillip Masters
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Fantastic Four No. 8 (Nov. 1962)
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Stan Lee Jack Kirby
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An artist that can control people with puppets he creates in their image using special radioactive clay. Is the step-father of Alicia Masters, Ben Grimm's future wife.
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Impossible Man
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Fantastic Four No. 11 (Feb 1963)
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Stan Lee Jack Kirby
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An alien that can shapeshift from the planet Poppup. He has a hivemind containing all the consciousnesses of Poppup before it was consumed by Galactus.[3]
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Red Ghost and his Super-Apes
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Ivan Kragoff
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Fantastic Four No. 13 (April 1963)
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Stan Lee Jack Kirby
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A ghost-like figure with three super-powered primates. A Soviet scientist who uses the same technology as the Fantastic Four to make it to the moon.
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Mad Thinker and his Awesome Android
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Julius
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Fantastic Four No. 15 (Jun 1963)
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Stan Lee Jack Kirby
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A genius specializing in evil robotics who usually comes up with very elaborate, infallible, devious plans that unfold like clockwork.
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Super-Skrull
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Kl'rt
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Fantastic Four No. 18 (Sep. 1963)
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Stan Lee Jack Kirby
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A Skrull with the combined powers of the Fantastic Four and also hypnosis.
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Rama-Tut
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Nathaniel Richards
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Fantastic Four No. 19 (Oct. 1963)
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Stan Lee Jack Kirby
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One of the many names of Kang the Conqueror, an Avengers villain and Reed Richard's descendant.
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Molecule Man
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Owen Reece
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Fantastic Four No. 20 (November 1963)
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Stan Lee Jack Kirby
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A villain or a reluctant hero with the power of molecular manipulation. Originally could only control inorganic matter, but can now control organic matter as well.
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Hate-Monger
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Clone of Adolf Hitler
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Fantastic Four No. 21 (December 1963)
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Stan Lee Jack Kirby
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Infant Terrible
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Fantastic Four No. 24 (March 1964)
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Stan Lee Jack Kirby
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Diablo
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Esteban Corazón de Ablo
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Fantastic Four No. 30 (September 1964)
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Stan Lee Jack Kirby
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An evil alchemist from medieval Spain who controls the Four Elements
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Attuma
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Fantastic Four No. 33 (December 1964)
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Stan Lee Jack Kirby
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An Atlantean who is also Namor's archenemy.
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Dragon Man
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Fantastic Four No. 35 (February 1965).
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Stan Lee Jack Kirby
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A robot in the form of a humanoid dragon that was brought to life by Diablo. He later gains intelligence and sentience, becoming an ally and teacher to the Future Foundation.
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Frightful Four
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Fantastic Four No. 36 (March 1965)
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Stan Lee Jack Kirby
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The evil version of the Fantastic Four. Led by the Human Torch's enemy Wizard. The lineup frequently changes, with founding members Wizard, Medusa, Sandman, and Paste-Pot Pete.
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Maximus the Mad
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Maximus Boltagon
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Fantastic Four No. 47 (Feb. 1966)
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Stan Lee Jack Kirby
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A member of the Inhumans who wants to take over his brother and archenemy Black Bolt's reign as ruler of the Inhumans.
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Galactus
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Fantastic Four No. 48 (March 1966)
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Stan Lee Jack Kirby
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A gigantic cosmic entity that feeds on planets. Also the Silver Surfer's archenemy and frequent master.
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Klaw
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Ulysses Klaue
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Fantastic Four No. 56 (Nov 1966)
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Stan Lee Jack Kirby
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A human physicist who has been transformed into solid sound and who wears a sonic emitter on his right wrist as a prosthetic device. Also known as an enemy of Black Panther.
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Blastaar
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Fantastic Four No. 62 (May 1967)
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Stan Lee Jack Kirby
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A villain from the Negative Zone with the power to project blasts of highly concussive kinetic force from his hands.
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Ronan the Accuser
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Fantastic Four No. 65 (Aug. 1967)
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Stan Lee Jack Kirby
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The Supreme Accuser of the Kree Empire.
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Kree
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Fantastic Four No. 65 (Aug. 1967)
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Stan Lee Jack Kirby
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A scientifically and technologically advanced militaristic alien race.
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Psycho-Man
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Fantastic Four Annual No. 5 (Nov. 1967)
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Stan Lee Jack Kirby
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A member of a microscopic race who can manipulate emotions.
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Annihilus
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Fantastic Four Annual No. 6 (November 1968)
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Stan Lee Jack Kirby
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A villain from the Negative Zone that wields a cosmic control rod to take over the Earth.
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Overmind
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Fantastic Four No. 113 (August 1971)
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Stan Lee John Buscema
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An alien belonging to the Eternals.
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Air-Walker
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Gabriel Lan
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Fantastic Four No. 120 (March 1972)
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Stan Lee John Buscema
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The Xandarian Herald of Galactus.
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Nicholas Scratch
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Fantastic Four No. 185 (August 1977)
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Len Wein George Pérez
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A wizard and the son of Fantastic Four supporting character Agatha Harkness.
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Salem's Seven
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Fantastic Four No. 186 (September 1977)
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Len Wein George Pérez
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A team of seven magical supervillains that are children of Nicholas Scratch and grandchildren of Agatha Harkness.
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Terrax the Tamer
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Tyros
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Fantastic Four No. 211 (Oct. 1979)
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Marv Wolfman John Byrne Joe Sinnott Ben Sean
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A Herald of Galactus who later betrayed him.
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Karisma
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Mary Brown
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Fantastic Four #266 (May, 1984)
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John Byrne
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Mary Brown is a supervillain who uses radiation wavelengths to become irresistible to men.
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Kristoff Vernard
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Kristoff von Doom
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Fantastic Four No. 247 (October 1982)
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John Byrne
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Someone who takes the identity of Doctor Doom for a while before becoming an ally for the Fantastic Four. Originally Doctor Doom's heir apparent.
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Terminus
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Fantastic Four No. 269 (August 1984)
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John Byrne
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An alien destroyer.
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Fasaud
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Fantastic Four No. 308 (November 1987)
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Steve Englehart and John Buscema
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A man transformed into a living electronic image.
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Paibok the Power Skrull
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Fantastic Four No. 358 (November 1991)
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Tom DeFalco Paul Ryan Danny Bulanadi
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A powerful Skrull.
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Devos the Devastator
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Fantastic Four No. 359 (December 1991)
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Tom DeFalco Paul Ryan Danny Bulanadi
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An extraterrestrial vigilante dedicated to bringing peace to the universe, but holds the rather warped view that this can only be done by destroying anyone whom he deems a threat to galactic peace.
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Occulus
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Fantastic Four No. 363 (Apr 1992)
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Tom DeFalco Paul Ryan
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One of the first villains imprisoned in the Negative Zone prison.
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Hyperstorm
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Johnathon Richards
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Fantastic Four No. 406 (November 1995)
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Tom DeFalco Paul Ryan Dan Bulanadi
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Reed and Sue's grandson from the future and an enemy of the Fantastic Four.
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Abraxas
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Fantastic Four Annual 2001 (September 2001)
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Carlos Pacheco
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A cosmic entity who seeks to destroy all realities.
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Salamandra
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Fantastic Four No. 514 (August 2004)
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Paco Medina
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A half-human/half-dragon woman who is the Wizard's ex-wife.
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Quiet Man
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possibly "John Eden"
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Fantastic Four Vol. 5 No. 5 (July 2014)
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James Robinson Leonard Kirk
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A genius level intellect who considers himself Reed's arch-rival.
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Victorious
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Zora Vukovic
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Fantastic Four Vol. 6 No. 1 (October 2018)
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Dan Slott Simone Bianchi
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A dedicated patriot and freedom fighter in her homeland of Latveria, she was given cosmic powers bestowed by Doctor Doom.
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