Methoxypiperamide

Methoxypiperamide
Legal status
Legal status	AU: S9 (Prohibited substance); EU: List I (Hungary);
Identifiers
	IUPAC name (4-Methoxyphenyl)(4-methylpiperazin-1-yl)methanone;
CAS Number	67023-02-3;
PubChem CID	805654;
ChemSpider	704980;
UNII	QD2GQ3VGF4;
CompTox Dashboard (EPA)	DTXSID501032899 ;
Chemical and physical data
Formula	C13H18N2O2
Molar mass	234.299 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC1=CC=C(C=C1)C(=O)N2CCN(CC2)C;
	InChI InChI=1S/C13H18N2O2/c1-14-7-9-15(10-8-14)13(16)11-3-5-12(17-2)6-4-11/h3-6H,7-10H2,1-2H3; Key:DWPVVZZGGGCRRM-UHFFFAOYSA-N;

Methoxypiperamide (also known as MeOP and MEXP) is a psychoactive drug of the piperazine class that has been sold online as a designer drug.^[1]^[2] It is the 4-methoxy-α-keto analog of methylbenzylpiperazine.

Very little data exists about the pharmacology and toxicity of methoxypiperamide; however, the US state of Vermont classifies it as a hallucinogen.

Legal status

Methoxypiperamide is a controlled substance in Vermont as of January 2016,^[3] and also in Hungary.^[4]

^ Power JD, Scott KR, Gardner EA, Curran McAteer BM, O'Brien JE, Brehon M, et al. (January 2014). "The syntheses, characterization and in vitro metabolism of nitracaine, methoxypiperamide and mephtetramine". Drug Testing and Analysis. 6 (7–8): 668–675. doi:10.1002/dta.1616. PMID 24574100.
^ Meyer MR, Holderbaum A, Kavanagh P, Maurer HH (October 2015). "Low resolution and high resolution MS for studies on the metabolism and toxicological detection of the new psychoactive substance methoxypiperamide (MeOP)". Journal of Mass Spectrometry. 50 (10): 1163–1174. Bibcode:2015JMSp...50.1163M. doi:10.1002/jms.3635. PMID 26456786.
^ "Regulated Drugs Rule" (PDF). Vermont Department of Health. Archived from the original (PDF) on 5 June 2016. Retrieved 14 October 2015.
^ "A Magyarországon megjelent, a Kábítószer és Kábítószer-függőség Európai Megfigyelő Központjának Korai Jelzőrendszerébe (EMCDDA EWS) 2005 óta bejelentett ellenőrzött anyagok büntetőjogi vonatkozású besorolása" [Criminal law classification of controlled substances published in Hungary and reported to the Early Warning System of the European Monitoring Center for Drugs and Drug Addiction (EMCDDA EWS) since 2005] (PDF). Daath (Hungarian Psychedelic Society) (in Hungarian). 3 September 2015.

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