The Midwest League began as the Illinois State League (1947–1948) and then became the Mississippi–Ohio Valley League (1949–1955). In 1956, the Mississippi–Ohio Valley League was renamed the Midwest League.[1][2] The circuit temporarily operated for the 2021 season as the High-A Central before reassuming its original moniker in 2022.
In 1960, the Davenport, Iowa based Quad City Braves joined the league as an expansion team. In 1962, Appleton, Burlington, and Cedar Rapids joined the Midwest League from the Illinois-Indiana-Iowa League which folded operations when those franchises switched leagues.[2] All those franchised remain in the league today. In 1963, the Midwest League was designated as a Class A league, after the minor league classification structure was reorganized.[4]
In 1976, the Midwest League contracted from ten teams to eight, as franchises in Danville and Dubuque were eliminated. In 1982, the league expanded from 8 to 12 teams, adding the Beloit Brewers, the Danville Suns, the Madison Muskies, and the Springfield Cardinals. The Peoria Suns relocated from Danville in 1983, and acquired their current name, Peoria Chiefs, the following year. In 1988, the league began splitting its season into two halves and expanded from 12 to 14 teams, with the addition of franchises in South Bend, Indiana, and Rockford, Illinois. During the 1990s several teams changed cities as Major League Baseball placed higher standards on minor league baseball facilities; franchises in smaller cities were sold to new owners who moved those teams to new ballparks in larger cities. Kenosha, Madison, Rockford, Springfield, Waterloo, and Wausau lost teams during this decade while Battle Creek, Dayton, Fort Wayne, Grand Rapids (West Michigan), Kane County, and Lansing gained teams.[2]
The 1978 Appleton Foxes are ranked #93 on the Top-100 All Time teams by MiLB.com.[6] Led by future Cy Young Award winner LaMarr Hoyt, the team finished 97–40. Harry Chappas, Ross Baumgarten and Britt Burns were all called up to the parent Chicago White Sox at the conclusion of the MWL season. The 97 wins by the Foxes remains a Midwest League record.[6]
The start of the 2020 season was postponed due to the COVID-19 pandemic before ultimately being cancelled on June 30.[8][9]
As part of Major League Baseball's 2021 reorganization of the minor leagues, the Midwest League was promoted to High-A, reduced to 12 teams, and temporarily renamed the "High-A Central" for the 2021 season.[10] Following MLB's acquisition of the rights to the names of the historical minor leagues, the High-A Central was renamed the Midwest League effective with the 2022 season.[11]