Occupational exposure to chemicals, dusts, radiation, and certain industrial processes have been tied to occupational cancer. Exposure to cancer-causing chemicals (carcinogens) may cause mutations that allow cells to grow out of control, causing cancer. Carcinogens in the workplace may include chemicals like anilines, chromates, dinitrotoluenes, arsenic and inorganic arsenic compounds, beryllium and beryllium compounds, cadmium compounds, and nickel compounds.[1] Dusts that can cause cancer leather or wood dusts, asbestos,[2] crystalline forms of silica, coal tar pitch volatiles, coke oven emissions, diesel exhaust and environmental tobacco smoke.[1]sunlight; radon gas; and industrial, medical, or other exposure to ionizing radiation can all cause cancer in the workplace. Industrial processes associated with cancer include aluminum production; iron and steel founding; and underground mining with exposure to uranium or radon. Shift work, which can disturb the circadian rhythm, has also been identified as a risk factor for some forms of cancer, in particular for breast cancer. [3][4][5]
Personal characteristics such as age, sex, and race
Family history of cancer
Being overweight or having obesity
Diet and personal habits such as tobacco use and alcohol consumption
The presence of certain medical conditions or past medical treatments, including chemotherapy, radiation treatment, or some immune-system suppressing drugs
Firefighters have shown higher rates of certain types of cancer (respiratory, digestive, and urinary systems), and of all cancers combined, when compared to the general U.S. population.[9] This is linked to many aspects of the firefighting occupation such as exposure to smoke and other products of combustion that are known carcinogens, as well as being exposed to chemicals in the gear worn to protect the firefighter. [10]
The increased levels of dust and chemicals like asbestos at construction sites leads to workers being exposed. These long term exposures have been linked to the development of lung cancer.[19] Other factors related to construction work can also put the workers at an elevated risk of cancer such as sun exposure. Construction workers are often required to spend long hours working in the sun. Long periods of exposure to radiation from the sun can cause skin cancer.[20][21]
Similar to construction workers, agricultural workers are exposed too many chemicals including known carcinogens. Workers in the agricultural field are also subject to long periods of exposure to radiation from the sun. All of these factors combine put the workers at and increased risk of developing cancers such as prostate cancer, multiple myeloma, and melanoma of the skin.[22]
Epidemiology
An estimated 48,000 cancers are diagnosed yearly in the US that come from occupational causes; this represents approximately 4-10% of total cancer in the United States.[23] It is estimated that 19% of cancers globally are attributed to environmental exposures (including work-related exposures).[24] It is estimated that there are approximately 120,000 work-related cancer cases annually in the EU due to exposure to carcinogens at work.[25]
Prevention
Many occupational cancers are preventable. Personal protective gear, workplace controls, and worker education can prevent exposure to carcinogens in the workplace. Tobacco smoking has also been shown to increase the risk of work-related cancers; decreasing or abstaining from smoking can decrease cancer risk.[2]
^Megdal SP, Kroenke CH, Laden F, Pukkala E, Schernhammer ES (September 2005). "Night work and breast cancer risk: a systematic review and meta-analysis". European Journal of Cancer. 41 (13): 2023–2032. doi:10.1016/j.ejca.2005.05.010. PMID16084719.
