The men's 100m freestyle S10 event at the 2012 Summer Paralympics took place at the London Aquatics Centre on 6 September. There were three heats; the swimmers with the eight fastest times advanced to the final.
Competed from 11:33.
Competed at 20:20.
Q = qualified for final. PR = Paralympic Record. EU = European Record. AS = Asian Record. AF = African Record. OC = Oceania Record.
Official London 2012 Paralympics Results: Heats Archived 2012-09-13 at the Wayback Machine Official London 2012 Paralympics Results: Final Archived 2012-09-13 at the Wayback Machine