This was the first WEC event to exclusively feature fights in the lightweight, featherweight, and bantamweight weight classes. The organization's heavier weight classes had been folded into the UFC over the previous four months. World Extreme Cagefighting would maintain this weight class structure for the remainder of the promotion's existence.
WEC Bantamweight Champion Miguel Torres was to defend his title against Brian Bowles at this event, but Bowles was forced to withdraw from the bout due to a back injury, and was replaced by WEC newcomer Takeya Mizugaki.[2] The Torres/Bowles bout was rescheduled for WEC 42 that August, where Bowles won the title by knockout.
Early reports suggested that Wagnney Fabiano could face former WEC Featherweight Champion Urijah Faber at this event, though he was later confirmed to be facing Fredson Paixao instead.[3]
Cole Province was originally slated to face Rafael Dias at this event, but bowed out due to an injury and was replaced by Mike Budnik.[4]
A featherweight bout between Cub Swanson and Diego Nunes was once scheduled for this card, but was cancelled after Nunes suffered a hand injury three days prior to the event.[5]
The event drew an estimated 470,000 viewers on Versus.[6]
^Cruz landed an illegal knee to the head of Lopez while he was on the ground at 3:24 of round 3. Since Lopez was unable to continue, the bout was stopped and went to the scorecards.[7]