Share to:

CCR5

CCR5
Egitura erabilgarria
PDBOrtologoaren bilaketa: PDBe RCSB
Identifikatzaileak
AliasakCCR5 (HUGO), CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22, C-C motif chemokine receptor 5 (gene/pseudogene), C-C motif chemokine receptor 5
Kanpoko IDakOMIM: 601373   MGI: 107182   HomoloGene: 37325   GeneCards: CCR5   OMA: CCR5 - orthologs
Genetikoki lotutako gaixotasunak
type 1 diabetes mellitus 22 Itzul dezakezu, HIV infection Itzul dezakezu [1]
Drogaren xedea
aplaviroc Itzul dezakezu, cenicriviroc Itzul dezakezu, Marabirok, vicriviroc Itzul dezakezu, aplaviroc hydrochloride Itzul dezakezu, AZD5672 Itzul dezakezu [2]
Wikidata
Ikusi/Editatu giza geneaIkusi/Editatu saguaren genea

5 motako C-C kimiokina hartzailea, CCR5 deitua, CD4 T linfozitoen eta beste zelula immunogai batzuen gainazaleko hartzailea da. R5 motako GIB birusek kohartzaile gisa erabiltzen dute zelula ostalaria infektatzeko, ezinbestez CD4 hartzailea lotzeaz gain.[7]. Mintzeko proteina integralen kimiokina beten hartzaile-familiaren kidea da.[8]

Erreferentziak

  1. Genetikoki lotutako gaixotasunak CCR5ikusi/editatu erreferentziak Wikidatan. .
  2. Fisikoki elkarreragiten duten drogak CCR5ikusi/editatu erreferentziak Wikidatan. .
  3. a b c GRCh38: Ensembl release 89: ENSG00000160791 - Ensembl, May 2017
  4. a b c GRCm38: Ensembl release 89: ENSMUSG00000079227Ensembl, May 2017
  5. Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
  6. Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
  7. Euskalterm: [Hiesa Hiztegia] [2016]
  8. Samson M, Labbe O, Mollereau C, Vassart G, Parmentier M. (1996ko martxoa). «Molecular cloning and functional expression of a new human CC-chemokine receptor gene» Biochemistry 35 (11): 3362–7.  doi:10.1021/bi952950g. PMID 8639485..

Kanpo estekak

Content Disclaimer

Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.

  1. The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
  2. There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
  3. It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
  4. Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
  5. Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.
Prefix: a b c d e f g h i j k l m n o p q r s t u v w x y z 0 1 2 3 4 5 6 7 8 9

Portal di Ensiklopedia Dunia

Kembali kehalaman sebelumnya