Zonulina
Zonulina digestio-aparatuan eta bereziki hesteetan jarduten duen proteina da, markatzaile gisa hainbat gaixotasunen diagnostikoan (gaitz autoimmuneak, minbizia...) bilatzen dena. 2000. urtean aurkitu zuen Alessio Fasano ikerlari italiarrak.
Zonulinak zeregin oso garrantzitsua betetzen du heste-iragazkortasunean, heste-hormaren zeluletako lotura estuak lasaitzen dituelako. Ondorioz, elikagaien igarotzea errazten du, hesteetatik odolera pasatzen diren substantzien mugimendua proteina honen jarduerapean dago hein handi batean.
Zonulinaren gehiegizko jarduerak heste-iragazkortasunaren areagotzea eragiten du. Horrek ondorio gaiztoak ekar ditzake, odolera pasatu behar ez liratekeen makromolekulak pasatu daitezkeelako, eta horrek gaixotasun autoimmuneak, infekzioak eta minbizi mota batzuk eragin ditzake[1] [2]
Erreferentziak
- ↑ Fasano, A (2011 Jan) Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer Physiol Rev 91 (1): 151-75.
- ↑ Identifican una estrategia preventiva que podría frenar el inicio de la artritis Clínic Barcelona (2015)
Kanpo estekak
| Autoritate kontrola |
|
|---|
Datuak: Q8074021
Content Disclaimer
Informasi ini disarikan dari Wikipedia dan disajikan kembali untuk tujuan edukasi. Konten tersedia di bawah lisensi CC BY-SA 3.0. Kami tidak bertanggung jawab atas ketidakakuratan data yang bersumber dari kontribusi publik tersebut.
- The information displayed on this website is sourced in part or in whole from Wikipedia and has been adapted for the purpose of restating it. We strive to provide accurate and relevant information, however:
- There is no guarantee of absolute accuracy. Wikipedia is an open, collaborative project that can be edited by anyone, so information is subject to change.
- It is not intended to constitute professional advice. The content displayed is for informational and educational purposes only. For important decisions (e.g., medical, legal, or financial), please consult a professional.
- Content copyright. Wikipedia is licensed under the Creative Commons Attribution-ShareAlike License (CC BY-SA). This means that content may be reused with appropriate attribution and shared under a similar license.
- Responsible use. Any risk arising from the use of information from this website is entirely the responsibility of the user.
