Tenoksiksam
 | |
| Klinični podatki | |
|---|---|
| AHFS/Drugs.com | International Drug Names |
| Način uporabe | skozi usta |
| Oznaka ATC | |
| Pravni status | |
| Pravni status | |
| Farmakokinetični podatki | |
| Vezava na beljakovine | visoka |
| Razpolovni čas | 30–140 h |
| Identifikatorji | |
| |
| Številka CAS | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.149.365 |
| Kemični in fizikalni podatki | |
| Formula | C13H11N3O4S2 |
| Mol. masa | 337,37 g·mol−1 |
| Tališče | 209 do 213 °C (dec.) |
Tenoksikám, pod zaščitenim imenom Mobiflex in drugimi, je nesteroidna protivnetna učinkovina,[1] ki se uporablja za lajšanje vnetja, otekanja, okorelosti in bolečin pri revmatoidnem artritisu, osteoartritisu, ankilozirajočem spondilitisu (vrsta artritisa, ki prizadene hrbtenico), tendinitisu (vnetje kit), burzitisu (vnetje sluznikov oziroma burz ob sklepih) in periartritisa ramen ali kolkov (vnetje tkiv, ki obdajajo omenjene sklepe).[2]
Spada v skupino nesteroidnih protivnetnih zdravil, ki se imenujejo oksikami. Neselektivno zavira encim ciklooksigenazo (COX-1 in COX-2).[3]
Patentiralo ga je farmacevtsko podjetje Roche leta 1974, za klinično uporabo pa so ga odobrili leta 1987.[4] V Sloveniji zdravilo s tenoksikamom ni na voljo,[5] v več evropskih državah pa je na trgu v obliki zdravil na recept.[2][6]
Sklici
- ↑ https://www.termania.net/slovarji/slovenski-medicinski-slovar/5541207/tenoksikam?query=Tenoksikam&SearchIn=All, Slovenski medicinski e-slovar, vpogled: 11. 4. 2022.
- ↑ 2,0 2,1 »Medicines A-Z - Tenoxicam«. NHS. Arhivirano iz prvotnega spletišča dne 5. novembra 2015. Pridobljeno 3. julija 2015.
- ↑ Moore OA, McIntyre M, Moore RA, Derry S, McQuay HJ. Single dose oral tenoxicam for acute postoperative pain in adults. Cochrane Database Syst Rev. 2009 Jul 8;2009(3):CD007591. doi: 10.1002/14651858.CD007591.pub2. PMID: 19588438; PMCID: PMC4175441.
- ↑ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery (v angleščini). John Wiley & Sons. str. 519. ISBN 9783527607495.
- ↑ http://www.cbz.si/cbz/bazazdr2.nsf/Search?SearchView&Query=(%5BSIATCKLA%5D=M01AC02*)&SearchOrder=4&SearchMax=301#, Centralna baza zdravil, vpogled: 11. 4. 2022.
- ↑ »Drugs.com international listings for Tenoxicam«. Drugs.com. Pridobljeno 3. julija 2015.
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