Taxolo
| Taxolo | |
 | |
| Sostansa chìmega | tipo de entità chìmega |
|---|---|
| Masa | 853,331 u |
| Fòrmuła bruta o mołecołare | C47H51NO14 |
| Nùmaro CAS | |
| Nùmaro EINECS | 608-826-9 |
| Còdaze ATC | Errore script: la funzione "arraytostring" non esiste. |
| PubChem | 36314 |
| DrugBank | DBDB01229 |
| SMILES | CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C |
Al taxolo (pronuncià Tacsolo) al ze an conposto doperà de sti tenpi pì che sia in chemioterapia par al tratamento de i tumor. Al taxolo al ze na "droga" che la ga an efeto de stabilizasion su i microtubui parchè la cadena lateral de sta molecola la ze in grado de interagir co i microtubui. Al altera al equilibrio de polimerizasion/depolimerizasion de i microtubui provocando la formasion de struture microtubulari tanto stàbiłi e de conseguensa alternado i mecanismi ch ei regola al ciclo celular. Al taxolo al gnen cavà da la scorsa del pola de nass, la atività "tossica" de i tassoidi (cossì i se ciama i conposti che gnen da i pola de nass) la era belche cognossesta a i tenpi de i Romani, come che se desume da i scriti del 51 a.C. (De Bello Gallico) come velen mortal. Inte la Amèrica del Nord-Est tribù indigene le usea estrati de la scorsa de la pola de nass mericana come desinfetante, abortiu e contro al melanoma.
| Controło de autorità | LCCN (EN) sh92003700 · GND (DE) 4351511-3 · BNE (ES) XX554373 (data) |
|---|
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