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Peruvoside

Peruvoside
Dữ liệu lâm sàng
Đồng nghĩa(3S,5R,10R,13R,14S,17R)- 3-[(2S,5R)- 3,5-dihydroxy- 4-methoxy- 6-methyloxan- 2-yl]oxy- 14-hydroxy- 13-methyl- 17-(5-oxo-2H-furan-3-yl)- 1,2,3,4,5,6,7,8,9,11,12,15,16,17- tetradecahydrocyclopenta[a]phenanthrene- 10-carbaldehyde
Mã ATC
Các định danh
Tên IUPAC
  • (3β,5β,8ξ,9ξ)- 3-[(6-deoxy- 3-O-methyl- α-D- glycero- hexopyranosyl)oxy]- 14-hydroxy- 19-oxocard- 20(22)enolide
Số đăng ký CAS
PubChem CID
ChemSpider
ChEMBL
ECHA InfoCard100.013.327
Dữ liệu hóa lý
Công thức hóa họcC30H44O9
Khối lượng phân tử548.665 g/mol
Mẫu 3D (Jmol)
SMILES
  • O=C\1OC/C(=C/1)[C@H]6CC[C@@]5(O)[C@]6(C)CC[C@H]3[C@H]5CC[C@@H]4C[C@@H](O[C@@H]2O[C@@H](C)[C@H](O)[C@@H](OC)[C@@H]2O)CC[C@]34C=O
Định danh hóa học quốc tế
  • InChI=1S/C30H44O9/c1-16-24(33)26(36-3)25(34)27(38-16)39-19-6-10-29(15-31)18(13-19)4-5-22-21(29)7-9-28(2)20(8-11-30(22,28)35)17-12-23(32)37-14-17/h12,15-16,18-22,24-27,33-35H,4-11,13-14H2,1-3H3/t16-,18+,19-,20+,21-,22+,24-,25-,26+,27-,28+,29+,30-/m0/s1 checkY
  • Key:PMTSPAGBAFCORP-HBUONDEYSA-N checkY
  (kiểm chứng)

Peruvoside (hoặc cannogenin thevetoside) là một glycoside tim [1] cho bệnh suy tim.[2]

Nó có nguồn gốc từ Cascabela thevetia (Thevetia neriifolia).[2]

Tham khảo

  1. ^ Arora, R. B.; Rangaswami, S. (1972). Peruvoside and Other Cardiotonic Glycoside[s] of Thevetia neriifolia Juss: Chemical, Pharmacological, and Clinical Studies. New Delhi, India: Thomson. LCCN 78900408.
  2. ^ a b Bhatia, M. L.; Manchanda, S. C.; Roy, S. B. (1970). "Haemodynamic Studies with Peruvoside in Human Congestive Heart Failure". British Medical Journal. Quyển 3 số 5725. tr. 740–743. doi:10.1136/bmj.3.5725.740. PMC 1701679. PMID 4919553.

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