TNP1
| TNP1 | |||||||
|---|---|---|---|---|---|---|---|
| معرفات | |||||||
| أسماء بديلة | TNP1, TP1, transition protein 1 | ||||||
| معرفات خارجية | الوراثة المندلية البشرية عبر الإنترنت 190231 MGI: MGI:98784 HomoloGene: 136517 GeneCards: 7141 | ||||||
| نمط التعبير عن الحمض النووي الريبوزي | |||||||
 |
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| المزيد من بيانات التعبير المرجعية | |||||||
| تماثلات متسلسلة | |||||||
| أنواع | الإنسان | الفأر | |||||
| أنتريه | 7141 | 21958 | |||||
| Ensembl | ENSG00000118245 | ENSMUSG00000026182 | |||||
| يونيبروت | |||||||
| RefSeq (رنا مرسال.) | |||||||
| RefSeq (بروتين) | |||||||
| الموقع (UCSC | n/a | Chr 1: 73.05 – 73.06 Mb | |||||
| بحث ببمد | [1] | [2] | |||||
| ويكي بيانات | |||||||
| |||||||
TNP1 (Transition protein 1) هوَ بروتين يُشَفر بواسطة جين TNP1 في الإنسان.[1][2]
الوظيفة
![[أيقونة]](https://infokontak.com/ar/%D9%85%D9%84%D9%81:Crystal_xedit.svg){kind=small} | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
| هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ Luerssen H، Mattei MG، Schroter M، Grzeschik KH، Adham IM، Engel W (يناير 1991). "Nucleotide sequence of the gene for human transition protein 1 and its chromosomal localization on chromosome 2". Genomics. ج. 8 ع. 2: 324–30. DOI:10.1016/0888-7543(90)90289-7. PMID:2249851.
- ^ "Entrez Gene: TNP1 transition protein 1 (during histone to protamine replacement)". مؤرشف من الأصل في 2010-12-05.
قراءة متعمقة
- Meistrich ML، Mohapatra B، Shirley CR، Zhao M (2004). "Roles of transition nuclear proteins in spermiogenesis". Chromosoma. ج. 111 ع. 8: 483–8. DOI:10.1007/s00412-002-0227-z. PMID:12743712.
- Chirat F، Martinage A، Briand G، وآخرون (1991). "Nuclear transition protein 1 from ram elongating spermatids. Mass spectrometric characterization, primary structure and phosphorylation sites of two variants". Eur. J. Biochem. ج. 198 ع. 1: 13–20. DOI:10.1111/j.1432-1033.1991.tb15980.x. PMID:2040274.
- Baskaran R، Rao MR (1991). "Interaction of spermatid-specific protein TP2 with nucleic acids, in vitro. A comparative study with TP1". J. Biol. Chem. ج. 265 ع. 34: 21039–47. PMID:2250010.
- Kleene KC، Borzorgzadeh A، Flynn JF، وآخرون (1988). "Nucleotide sequence of a cDNA clone encoding mouse transition protein 1". Biochim. Biophys. Acta. ج. 950 ع. 2: 215–20. DOI:10.1016/0167-4781(88)90013-9. PMID:3382664.
- Luerssen H، Hoyer-Fender S، Engel W (1988). "The nucleotide sequence of human transition protein 1 cDNA". Nucleic Acids Res. ج. 16 ع. 15: 7723. DOI:10.1093/nar/16.15.7723. PMC:338445. PMID:3412903.
- Akama K، Kojima S، Nakano M، وآخرون (1994). "The amino acid sequence and phosphorylation sites of a boar transition protein 1". Biochem. Mol. Biol. Int. ج. 32 ع. 2: 349–57. PMID:8019440.
- Steger K، Klonisch T، Gavenis K، وآخرون (1999). "Expression of mRNA and protein of nucleoproteins during human spermiogenesis". Mol. Hum. Reprod. ج. 4 ع. 10: 939–45. DOI:10.1093/molehr/4.10.939. PMID:9809674.
- Yu YE، Zhang Y، Unni E، وآخرون (2000). "Abnormal spermatogenesis and reduced fertility in transition nuclear protein 1-deficient mice". Proc. Natl. Acad. Sci. U.S.A. ج. 97 ع. 9: 4683–8. DOI:10.1073/pnas.97.9.4683. PMC:18293. PMID:10781074.
- Siffroi JP، Alfonsi MF، Dadoune JP (2001). "Electron microscopic in situ hybridization study of simultaneous expression of TNP1 and PRM1 genes in human spermatids". Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia. ج. 103 ع. 4 Suppl 1: 65–74. PMID:11315969.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Miyagawa Y، Nishimura H، Tsujimura A، وآخرون (2006). "Single-nucleotide polymorphisms and mutation analyses of the TNP1 and TNP2 genes of fertile and infertile human male populations". J. Androl. ج. 26 ع. 6: 779–86. DOI:10.2164/jandrol.05069. PMID:16291974.
- Jedrzejczak P، Kempisty B، Bryja A، وآخرون (2007). "Quantitative assessment of transition proteins 1, 2 spermatid-specific linker histone H1-like protein transcripts in spermatozoa from normozoospermic and asthenozoospermic men". Arch. Androl. ج. 53 ع. 4: 199–205. DOI:10.1080/01485010701426430. PMID:17852044.
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