1cP-LSD

1cP-LSD
Clinical data
Other names	1cP, acid, LSD, Lucy
Dependence; liability	Low
Addiction; liability	None
Routes of; administration	By mouth, under the tongue
Legal status
Legal status	AU: S9 (Prohibited substance); BR: Class F2 (Prohibited psychotropics); CA: Unscheduled.; DE: NpSG (Industrial and scientific use only); UK: Under Psychoactive Substances Act;
Pharmacokinetic data
Onset of action	30 - 60 minutes
Duration of action	8 - 24 hours
Identifiers
	IUPAC name (6aR,9R)-N,N-diethyl-7-methyl-4-cyclopropylmethanoyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide;
CAS Number	2767597-50-0;
PubChem CID	155884675;
ChemSpider	107450612;
UNII	7UU7S6TN3J;
Chemical and physical data
Formula	C24H29N3O2
Molar mass	391.515 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCN(CC)C(=O)[C@@H]5C=C2[C@@H](Cc3cn(C(=O)C1CC1)c4cccc2c34)N(C)C5;
	InChI InChI=1S/C24H29N3O2/c1-4-26(5-2)23(28)17-11-19-18-7-6-8-20-22(18)16(12-21(19)25(3)13-17)14-27(20)24(29)15-9-10-15/h6-8,11,14-15,17,21H,4-5,9-10,12-13H2,1-3H3/t17-,21-/m1/s1; Key:RAFUPYYDHPFASC-DYESRHJHSA-N;

1cP-LSD (N1-(cyclopropylmethanoyl)-lysergic acid diethylamide) is an acylated derivative of lysergic acid diethylamide (LSD), which has been sold as a designer drug. ^[1]^[2] It was first synthesized as a legal-LSD alternative by Lizard Labs, a Netherlands based research chemical laboratory.^[3] In tests on mice it was found to be an active psychedelic with similar potency to 1P-LSD.^[4]

Legal status

Sweden's public health agency suggested classifying 1cP-LSD as a dangerous substance on 18 December 2019 and later classified it as such on 22 April 2021.^[5]^[6]

^ Tanaka R, Kawamura M, Hakamatsuka T, Kikura-Hanajiri R (2020). "[Identification of LSD Derivatives, 1cP-LSD, MIPLA and 1B-LSD in Illegal Products as Paper Sheet]". Yakugaku Zasshi. 140 (11): 1405–1413. doi:10.1248/yakushi.20-00124. PMID 33132277.
^ Vincenti F, Gregori A, Flammini M, Di Rosa F, Salomone A (July 2021). "Seizures of New Psychoactive Substances on the Italian territory during the COVID-19 pandemic". Forensic Science International. 326: 110904. doi:10.1016/j.forsciint.2021.110904. PMC 8411784. PMID 34371393.
^ spotlight (2018-07-25). "About Us - Lizard Labs". lizardlabs.nl. Retrieved 2024-09-13.
^ Brandt SD, Kavanagh PV, Westphal F, Stratford A, Odland AU, Klein AK, et al. (June 2020). "Return of the lysergamides. Part VI: Analytical and behavioural characterization of 1-cyclopropanoyl-d-lysergic acid diethylamide (1CP-LSD)". Drug Testing and Analysis. 12 (6): 812–826. doi:10.1002/dta.2789. PMC 9191646. PMID 32180350.
^ "Förordning (1999:58) om förbud mot vissa hälsofarliga varor".
^ "Tjugotre ämnen föreslås klassas som narkotika eller hälsofarlig vara" [Twenty-three substances are proposed to be classified as drugs or dangerous goods] (in Swedish). Folkhälsomyndigheten. December 18, 2019. Archived from the original on November 24, 2022. Retrieved May 28, 2020.

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