University of California, Los Angeles
Stanford University
Known for
Work on developing a Human Cell Atlas that characterizes the genetic material of every single cell in the body.
Awards
Chancellor’s Award for Advancing Institutional Excellence and Equity (CAAIEE)
UC Bioengineering Systemwide Shu Chien Early Career Award
Pew Biomedical Scholar
Scientific career
Fields
Bioengineering
Institutions
University of California, Berkeley
CZ Biohub
Aaron Michael Streets (November 16, 1981 – present) is an African American bioengineer and associate professor in the Department of Engineering at the University of California, Berkeley in Berkeley, California. He is the principal investigator at the Streets Lab, where he and his team use tools from mathematics, physics, and engineering to study biology.[1] Streets is currently developing microfluidic technology for single-cell measurements due to its high-resolution imaging.[2]
Education
In 2004, Streets received both a B.S. in Physics Magna Cum Laude and a B.A. in Art Magna Cum Laude from the University of California, Los Angeles. In 2012, he received his Doctor of Philosophy (Ph.D.) in Applied Physics from Stanford University.[3]
Career and research
Streets was a Whitaker International Postdoctoral Fellow and a Ford postdoctoral fellow and worked with Yanyi Huang in the Biodynamic Optical Imaging Center (BIOPIC) at Peking University as a postdoctoral researcher, in Beijing, China from 2012 to 2016.[4] In 2016, he accepted a position as a UC President's Postdoctoral Fellow at the University of California, San Francisco. Following his time there, he began working as an assistant professor in the Department of Bioengineering at the University of California, Berkeley from 2016 to 2022. In 2022, he received a promotion to associate professor at the University of California, Berkeley's Department of Bioengineering, where he still works today.[3]
Streets is currently a core faculty for the Center for Computational Biology, Berkeley Biophysics, and an investigator for Chan Zuckerberg Biohub in San Francisco, California.[5][6] He was recognized by Popular Science as one of the top up and coming scientists for his work on developing a Human Cell Atlas that characterizes the genetic material of every single cell in the body.[7] In addition to his roles in research and education, Streets promotes diversity and shows how being an African American scientist intersects with a duty to advance student success and the effectiveness of academic institutions through service.[8] Streets and the Chan Zuckerberg Biohub published a patent for microfluidic cell barcoding and sequencing in March 2023. This technology is used for high-resolution imaging of individual cells.[9] In addition, Streets is working to connect genomic data to the spatial organization of molecules and other morphological phenotypes that are more effectively probed with light, using the capabilities of high resolution imaging to make multimodal measurements on single cells.[2]
Awards and honors
2023
Chancellor's Award for Advancing Institutional Excellence and Equity (CAAIEE)
2021
UC Bioengineering Systemwide Shu Chien Early Career Award
NSF CAREER Award
2019
NSF CAREER award
Pew Biomedical Scholar
2017–2021
Chan Zuckerberg Biohub Investigator
2015
UC President's Postdoctoral Fellow
2014
Peking University Outstanding Postdoctoral Scholar
Ford Foundation Postdoctoral Fellow
2011
Whitaker International Biomedical Engineering Scholar
2009–2011
Stanford Vice Provost for Graduate Education Diversifying Academia and Recruiting Excellence (DARE) Fellowship
Publications
2023
Streets, Aaron M, Tyler Chen, et al.; University of California CZ Biohub SF LLC, assignee. Microfluidic Cell Barcoding and Sequencing. United States patent US-20230093891-A1, 30 March 2023.
2014
Streets, Aaron M, and Yanyi Huang. "How Deep Is Enough in Single-Cell RNA-Seq?" Nature Biotechnology, vol. 32, no. 10, 1 Oct. 2014, pp. 1005–1006, https://doi.org/10.1038/nbt.3039.
Streets, Aaron M., Ang Li, et al. "Imaging without Fluorescence: Nonlinear Optical Microscopy for Quantitative Cellular Imaging". Analytical Chemistry, vol. 86, no. 17, 1 Sep. 2014, pp. 8506–8513, https://doi.org/10.1021/ac5013706.
Streets, Aaron M., Xiannian Zhang, et al. "Microfluidic Single-Cell Whole-Transcriptome Sequencing". Proceedings of the National Academy of Sciences, vol. 111, no. 19, 1 May 2014, pp. 7048–7053, https://doi.org/10.1073/pnas.1402030111.
Streets, Aaron M, and Yanyi Huang. "Microfluidics for Biological Measurements with Single-Molecule Resolution". Current Opinion in Biotechnology, vol. 25, 1 Feb. 2014, pp. 69–77, https://doi.org/10.1016/j.copbio.2013.08.013.
2013
Streets, Aaron M., and Yanyi Huang. "Chip in a Lab: Microfluidics for next Generation Life Science Research". Biomicrofluidics, vol. 7, no. 1, 1 Jan. 2013, p. 011302, https://doi.org/10.1063/1.4789751.
Streets, Aaron M., Yannick Sourigues, et al. "Simultaneous Measurement of Amyloid Fibril Formation by Dynamic Light Scattering and Fluorescence Reveals Complex Aggregation Kinetics". PLoS ONE, vol. 8, no. 1, 17 Jan. 2013, https://doi.org/10.1371/journal.pone.0054541.
2012
Streets, Aaron Michael, Stephen Ronald Quake, et al. "Microfluidic and OPTOFLUIDIC Investigation of Biological Macromolecule Phase Transitions". Stanford University, Stanford University ProQuest Dissertations Publishing, 2012, pp. 1–113.
2011
Kim, Soohong, Aaron M Streets, et al. "High-Throughput Single-Molecule OPTOFLUIDIC Analysis". Nature Methods, vol. 8, no. 3, 1 Jan. 2011, pp. 242–245, https://doi.org/10.1038/nmeth.1569.
2010
Streets, Aaron M., and Stephen R. Quake. "Ostwald Ripening of Clusters during Protein Crystallization". Physical Review Letters, vol. 104, no. 17, 1 Jan. 2010, https://doi.org/10.1103/physrevlett.104.178102.
