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Deoxyinosine monophosphate

Deoxyinosine monophosphate
Names
IUPAC name
2’-Deoxy-5’-inosinic acid
Other names
dIMP
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard 100.020.216 Edit this at Wikidata
UNII
  • InChI=1S/C10H13N4O7P/c15-5-1-7(21-6(5)2-20-22(17,18)19)14-4-13-8-9(14)11-3-12-10(8)16/h3-7,15H,1-2H2,(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1
    Key: PHNGFPPXDJJADG-RRKCRQDMSA-N
  • InChI=1/C10H13N4O7P/c15-5-1-7(21-6(5)2-20-22(17,18)19)14-4-13-8-9(14)11-3-12-10(8)16/h3-7,15H,1-2H2,(H,11,12,16)(H2,17,18,19)/t5-,6+,7+/m0/s1
    Key: PHNGFPPXDJJADG-RRKCRQDMBF
  • O=C3/N=C\Nc1c3ncn1[C@@H]2O[C@@H]([C@@H](O)C2)COP(=O)(O)O
Properties
C10H13N4O7P
Molar mass 332.209 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Deoxyinosine monophosphate (dIMP) is a nucleoside monophosphate and a derivative of inosinic acid. It can be formed by the deamination of the purine base in deoxyadenosine monophosphate (dAMP). The enzyme deoxyribonucleoside triphosphate pyrophosphohydrolase, encoded by YJR069C in S. cerevisiae and containing (d)ITPase and (d)XTPase activities, hydrolyses dITP, resulting in the release of pyrophosphate and dIMP.[1]

See also

References

  1. ^ Davies O, Mendes P, Smallbone K, Malys N (2012). "Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism". BMB Reports. 45 (4): 259–64. doi:10.5483/BMBRep.2012.45.4.259. PMID 22531138.


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