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Ripazepam

Ripazepam
Identifiers
  • 1-ethyl-3-methyl-8-phenyl-4,6-dihydropyrazolo[4,3-e][1,4]diazepin-5-one
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H16N4O
Molar mass268.320 g·mol−1
3D model (JSmol)
  • CCN1C2=C(C(=N1)C)NC(=O)CN=C2C3=CC=CC=C3
  • InChI=1S/C15H16N4O/c1-3-19-15-13(10(2)18-19)17-12(20)9-16-14(15)11-7-5-4-6-8-11/h4-8H,3,9H2,1-2H3,(H,17,20) ☒N
  • Key:YFHYNLHGFKXAIQ-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Ripazepam is a pyrazolodiazepinone derivative structurally related to certain benzodiazepine drugs, especially zolazepam. It has anxiolytic effects.[1][2]

See also

References

  1. ^ Fitzgerald JE, de la Iglesia FA, McGuire EJ (April 1984). "Carcinogenicity studies in rodents and ripazepam, a minor tranquilizing agent". Fundamental and Applied Toxicology. 4 (2 Pt 1): 178–90. doi:10.1016/0272-0590(84)90118-0. hdl:2027.42/24852. PMID 6724192.
  2. ^ Baraldi PG, Manfredini S, Periotto V, Simoni D, Guarneri M, Borea PA (May 1985). "Synthesis and interaction of 5-(substituted-phenyl)-3-methyl-6,7-dihydropyrazolo[4,3-e] [1,4]diazepin-8(7H)-ones with benzodiazepine receptors in rat cerebral cortex". Journal of Medicinal Chemistry. 28 (5): 683–5. doi:10.1021/jm50001a025. PMID 2985787.
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