Stafford House is a mansion in the St. James's district in the West End of London.

Stafford House may also refer to:

in Canada

• Joseph Stafford House, listed on the Canadian Register of Historic Places

in the United Kingdom

• Stafford House College, a school in Canterbury, England
• Stafford House, Wrexham, building in Wrexham, Wales

in the United States

• Francis M. Stafford House, Paintsville, Kentucky
• Frederick H. and Elizabeth Stafford House, Port Hope, Michigan
• William R. Stafford House, Port Hope, Michigan
• Captain John H. Stafford House, Bronx, New York, a New York City Landmark
• John Stafford House, Columbus, Texas, formerly listed on the National Register of Historic Places

This disambiguation page lists articles associated with the title Stafford House.
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