P2RY2

No campo da biologia molecular, P2RY2 é uma proteína que pertence ao grupo dos receptores P2Y e que, em seres humanos, é codificada pelo gene P2RY2.^[1]^[2]

Referências

↑ Parr CE, Sullivan DM, Paradiso AM, Lazarowski ER, Burch LH, Olsen JC, Erb L, Weisman GA, Boucher RC, Turner JT (maio de 1994). «Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy». Proc Natl Acad Sci USA. 91 (8): 3275–9. PMC 43559. PMID 8159738
↑ Somers GR, Hammet F, Woollatt E, Richards RI, Southey MC, Venter DJ (novembro de 1997). «Chromosomal localization of the human P2y6 purinoceptor gene and phylogenetic analysis of the P2y purinoceptor family». Genomics. 44 (1): 127–30. PMID 9286708. doi:10.1006/geno.1997.4841

Leitura de apoio

Tokuyama Y, Hara M, Jones EM; et al. (1995). «Cloning of rat and mouse P2Y purinoceptors.». Biochem. Biophys. Res. Commun. 211 (1): 211–8. PMID 7779087. doi:10.1006/bbrc.1995.1798
Parr CE, Sullivan DM, Paradiso AM; et al. (1995). «Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.». Proc. Natl. Acad. Sci. U.S.A. 91 (26). 13067 páginas. PMC 45582. PMID 7809171. doi:10.1073/pnas.91.26.13067
Erb L, Lustig KD, Sullivan DM; et al. (1993). «Functional expression and photoaffinity labeling of a cloned P2U purinergic receptor.». Proc. Natl. Acad. Sci. U.S.A. 90 (22): 10449–53. PMC 47794. PMID 8248130. doi:10.1073/pnas.90.22.10449
Dasari VR, Sandhu AK, Mills DC; et al. (1996). «Mapping of the P2U purinergic receptor gene to human chromosome 11q 13.5-14.1.». Somat. Cell Mol. Genet. 22 (1): 75–9. PMID 8643996. doi:10.1007/BF02374378
Sullivan DM, Erb L, Anglade E; et al. (1997). «Identification and characterization of P2Y2 nucleotide receptors in human retinal pigment epithelial cells.». J. Neurosci. Res. 49 (1): 43–52. PMID 9211988. doi:10.1002/(SICI)1097-4547(19970701)49:1<43::AID-JNR5>3.0.CO;2-D
Bogdanov Y, Rubino A, Burnstock G (1998). «Characterisation of subtypes of the P2X and P2Y families of ATP receptors in the foetal human heart.». Life Sci. 62 (8): 697–703. PMID 9489506. doi:10.1016/S0024-3205(97)01168-5
Jin J, Dasari VR, Sistare FD, Kunapuli SP (1998). «Distribution of P2Y receptor subtypes on haematopoietic cells.». Br. J. Pharmacol. 123 (5): 789–94. PMC 1565225. PMID 9535005. doi:10.1038/sj.bjp.0701665
Tai CJ, Kang SK, Cheng KW; et al. (2000). «Expression and regulation of P2U-purinergic receptor in human granulosa-luteal cells.». J. Clin. Endocrinol. Metab. 85 (4): 1591–7. PMID 10770202. doi:10.1210/jc.85.4.1591
Erb L, Liu J, Ockerhausen J; et al. (2001). «An RGD sequence in the P2Y(2) receptor interacts with alpha(V)beta(3) integrins and is required for G(o)-mediated signal transduction.». J. Cell Biol. 153 (3): 491–501. PMC 2190579. PMID 11331301. doi:10.1083/jcb.153.3.491
Moore DJ, Chambers JK, Wahlin JP; et al. (2001). «Expression pattern of human P2Y receptor subtypes: a quantitative reverse transcription-polymerase chain reaction study.». Biochim. Biophys. Acta. 1521 (1-3): 107–19. PMID 11690642
Strausberg RL, Feingold EA, Grouse LH; et al. (2003). «Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.». Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. PMC 139241. PMID 12477932. doi:10.1073/pnas.242603899
Burrell HE, Bowler WB, Gallagher JA, Sharpe GR (2003). «Human keratinocytes express multiple P2Y-receptors: evidence for functional P2Y1, P2Y2, and P2Y4 receptors.». J. Invest. Dermatol. 120 (3): 440–7. PMID 12603858. doi:10.1046/j.1523-1747.2003.12050.x
Schafer R, Sedehizade F, Welte T, Reiser G (2003). «ATP- and UTP-activated P2Y receptors differently regulate proliferation of human lung epithelial tumor cells.». Am. J. Physiol. Lung Cell Mol. Physiol. 285 (2): L376–85. PMID 12691958. doi:10.1152/ajplung.00447.2002
Seye CI, Yu N, Jain R; et al. (2003). «The P2Y2 nucleotide receptor mediates UTP-induced vascular cell adhesion molecule-1 expression in coronary artery endothelial cells.». J. Biol. Chem. 278 (27): 24960–5. PMID 12714597. doi:10.1074/jbc.M301439200
Greig AV, Linge C, Terenghi G; et al. (2003). «Purinergic receptors are part of a functional signaling system for proliferation and differentiation of human epidermal keratinocytes.». J. Invest. Dermatol. 120 (6): 1007–15. PMID 12787128. doi:10.1046/j.1523-1747.2003.12261.x
Greig AV, Linge C, Healy V; et al. (2003). «Expression of purinergic receptors in non-melanoma skin cancers and their functional roles in A431 cells.». J. Invest. Dermatol. 121 (2): 315–27. PMID 12880424. doi:10.1046/j.1523-1747.2003.12379.x
Meshki J, Tuluc F, Bredetean O; et al. (2004). «Molecular mechanism of nucleotide-induced primary granule release in human neutrophils: role for the P2Y2 receptor.». Am. J. Physiol., Cell Physiol. 286 (2): C264–71. PMID 14613890. doi:10.1152/ajpcell.00287.2003
Haserück N, Erl W, Pandey D; et al. (2004). «The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors.». Blood. 103 (7): 2585–92. PMID 14645014. doi:10.1182/blood-2003-04-1127

Este artigo sobre Biologia molecular é um esboço. Você pode ajudar a Wikipédia expandindo-o.

[pmid8159738-1] Parr CE, Sullivan DM, Paradiso AM, Lazarowski ER, Burch LH, Olsen JC, Erb L, Weisman GA, Boucher RC, Turner JT (maio de 1994). «Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy». Proc Natl Acad Sci USA. 91 (8): 3275–9. PMC 43559. PMID 8159738

[pmid9286708-2] Somers GR, Hammet F, Woollatt E, Richards RI, Southey MC, Venter DJ (novembro de 1997). «Chromosomal localization of the human P2y6 purinoceptor gene and phylogenetic analysis of the P2y purinoceptor family». Genomics. 44 (1): 127–30. PMID 9286708. doi:10.1006/geno.1997.4841

[1]

[2]

P2RY2

Referências

Leitura de apoio

Information related to P2RY2

Portal di Ensiklopedia Dunia