ADAM18
| ADAM18 | |||||||||||||||||||||||||
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| Identifikatori | |||||||||||||||||||||||||
| Aliasi | ADAM18 | ||||||||||||||||||||||||
| Vanjski ID-jevi | MGI: 105986 HomoloGene: 74941 GeneCards: ADAM18 | ||||||||||||||||||||||||
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| Ortolozi | |||||||||||||||||||||||||
| Vrste | Čovjek | Miš | |||||||||||||||||||||||
| Entrez | |||||||||||||||||||||||||
| Ensembl | |||||||||||||||||||||||||
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| RefSeq (mRNK) | |||||||||||||||||||||||||
| RefSeq (bjelančevina) | |||||||||||||||||||||||||
| Lokacija (UCSC) | Chr 8: 39.58 – 39.73 Mb | Chr 8: 25.09 – 25.16 Mb | |||||||||||||||||||||||
| PubMed pretraga | [3] | [4] | |||||||||||||||||||||||
| Wikipodaci | |||||||||||||||||||||||||
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Protein 18 koji sadrži domenu dezintegrina i metaloproteinaze je enzim koji je kod ljudi kodiran genom ADAM18.[5][6]
Ovaj gen kodira člana porodice ADAM (domen dezintegrina i metaloproteinaze). Članovi ove porodice su proteini usidreni u membrane, strukturno srodni dezintegrinima zmijskog otrova, i uključeni su u različite biološke procese, kao što su interakcije ćelija-ćelija i ćelija-matriks, uključujući oplodnju, razvoj mišića i neurogenezu. Protein koji kodira ovaj gen je protein površine sperme.[6]
Reference
- ^ a b c ENSG00000278548 GRCh38: Ensembl release 89: ENSG00000168619, ENSG00000278548 - Ensembl, maj 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031552 - Ensembl, maj 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Frayne J, Hurd EA, Hall L (Aug 2002). "Human tMDC III: a sperm protein with a potential role in oocyte recognition". Mol Hum Reprod. 8 (9): 817–22. doi:10.1093/molehr/8.9.817. PMID 12200459.
- ^ a b "Entrez Gene: ADAM18 ADAM metallopeptidase domain 18".
Dodatna literatura
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Zhu GZ, Lin Y, Myles DG, Primakoff P (1999). "Identification of four novel ADAMs with potential roles in spermatogenesis and fertilization". Gene. 234 (2): 227–37. doi:10.1016/S0378-1119(99)00208-5. PMID 10395895.
- Frayne J, Jury JA, Barker HL, et al. (1998). "Macaque MDC family of proteins: sequence analysis, tissue distribution and processing in the male reproductive tract". Mol. Hum. Reprod. 4 (5): 429–37. doi:10.1093/molehr/4.5.429. PMID 9665629.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Vanjski linkovi
- The MEROPS online database for peptidases and their inhibitors: M12.957[mrtav link]
- Lokacija ljudskog genoma ADAM18 i stranica sa detaljima o genu ADAM18 u UCSC Genome Browseru.
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