FKBP8
FKBP8 (FK506 binding protein 8) هوَ بروتين يُشَفر بواسطة جين FKBP8 في الإنسان.[1][2]
الوظيفة
![[أيقونة]](https://infokontak.com/ar/%D9%85%D9%84%D9%81:Crystal_xedit.svg){kind=small} | هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
الأهمية السريرية
| هذا القسم فارغ أو غير مكتمل. ساهم في توسيعه. (يوليو 2018) |
المراجع
- ^ "Entrez Gene: FKBP8 FK506 binding protein 8, 38kDa". مؤرشف من الأصل في 2010-12-05.
- ^ Lam E، Martin M، Wiederrecht G (سبتمبر 1995). "Isolation of a cDNA encoding a novel human FK506-binding protein homolog containing leucine zipper and tetratricopeptide repeat motifs". Gene. ج. 160 ع. 2: 297–302. DOI:10.1016/0378-1119(95)00216-S. PMID:7543869.
قراءة متعمقة
- Bonaldo MF، Lennon G، Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. ج. 6 ع. 9: 791–806. DOI:10.1101/gr.6.9.791. PMID:8889548.
- Pedersen KM، Finsen B، Celis JE، Jensen NA (1999). "muFKBP38: a novel murine immunophilin homolog differentially expressed in Schwannoma cells and central nervous system neurons in vivo". Electrophoresis. ج. 20 ع. 2: 249–55. DOI:10.1002/(SICI)1522-2683(19990201)20:2<249::AID-ELPS249>3.0.CO;2-F. PMID:10197430.
- Hartley JL، Temple GF، Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. ج. 10 ع. 11: 1788–95. DOI:10.1101/gr.143000. PMC:310948. PMID:11076863.
- Wiemann S، Weil B، Wellenreuther R، وآخرون (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. ج. 11 ع. 3: 422–35. DOI:10.1101/gr.GR1547R. PMC:311072. PMID:11230166.
- Strausberg RL، Feingold EA، Grouse LH، وآخرون (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. ج. 99 ع. 26: 16899–903. DOI:10.1073/pnas.242603899. PMC:139241. PMID:12477932.
- Shirane M، Nakayama KI (2003). "Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis". Nat. Cell Biol. ج. 5 ع. 1: 28–37. DOI:10.1038/ncb894. PMID:12510191.
- Rosner M، Hofer K، Kubista M، Hengstschläger M (2003). "Cell size regulation by the human TSC tumor suppressor proteins depends on PI3K and FKBP38". Oncogene. ج. 22 ع. 31: 4786–98. DOI:10.1038/sj.onc.1206776. PMID:12894220.
- Grimwood J، Gordon LA، Olsen A، وآخرون (2004). "The DNA sequence and biology of human chromosome 19". Nature. ج. 428 ع. 6982: 529–35. DOI:10.1038/nature02399. PMID:15057824.
- Bulgakov OV، Eggenschwiler JT، Hong DH، وآخرون (2004). "FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues". Development. ج. 131 ع. 9: 2149–59. DOI:10.1242/dev.01122. PMID:15105374.
- Gerhard DS، Wagner L، Feingold EA، وآخرون (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. ج. 14 ع. 10B: 2121–7. DOI:10.1101/gr.2596504. PMC:528928. PMID:15489334.
- Wiemann S، Arlt D، Huber W، وآخرون (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. ج. 14 ع. 10B: 2136–44. DOI:10.1101/gr.2576704. PMC:528930. PMID:15489336.
- Rush J، Moritz A، Lee KA، وآخرون (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. ج. 23 ع. 1: 94–101. DOI:10.1038/nbt1046. PMID:15592455.
- Kang CB، Tai J، Chia J، Yoon HS (2005). "The flexible loop of Bcl-2 is required for molecular interaction with immunosuppressant FK-506 binding protein 38 (FKBP38)". FEBS Lett. ج. 579 ع. 6: 1469–76. DOI:10.1016/j.febslet.2005.01.053. PMID:15733859.
- Weiwad M، Edlich F، Erdmann F، وآخرون (2005). "A reassessment of the inhibitory capacity of human FKBP38 on calcineurin". FEBS Lett. ج. 579 ع. 7: 1591–6. DOI:10.1016/j.febslet.2004.12.098. PMID:15757646.
- Edlich F، Weiwad M، Erdmann F، وآخرون (2005). "Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin". EMBO J. ج. 24 ع. 14: 2688–99. DOI:10.1038/sj.emboj.7600739. PMC:1176465. PMID:15990872.
- Kang CB، Feng L، Chia J، Yoon HS (2005). "Molecular characterization of FK-506 binding protein 38 and its potential regulatory role on the anti-apoptotic protein Bcl-2". Biochem. Biophys. Res. Commun. ج. 337 ع. 1: 30–8. DOI:10.1016/j.bbrc.2005.09.023. PMID:16176796.
- Rual JF، Venkatesan K، Hao T، وآخرون (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. ج. 437 ع. 7062: 1173–8. DOI:10.1038/nature04209. PMID:16189514.
- Oh JH، Yang JO، Hahn Y، وآخرون (2006). "Transcriptome analysis of human gastric cancer". Mamm. Genome. ج. 16 ع. 12: 942–54. DOI:10.1007/s00335-005-0075-2. PMID:16341674.
- Mehrle A، Rosenfelder H، Schupp I، وآخرون (2006). "The LIFEdb database in 2006". Nucleic Acids Res. ج. 34 ع. Database issue: D415–8. DOI:10.1093/nar/gkj139. PMC:1347501. PMID:16381901.
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